How would you explain the significant elevations of uric acid on admission?

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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How would you explain the significant elevations of uric acid on admission?

CASE STUDY 12-2
A 3-year-old girl was admitted with a diagnosis of
acute lymphocytic leukemia. Her admitting labora-
tory data are shown in Case Study Table 12-2.1.
After admission, she was treated by administration of
packed red cells, 2 units of platelets, IV fluids, and
allopurinol. On the second hospital day, chemother-
apy was begun, using IV vincristine and prednisone
and intrathecal injections of methotrexate, predni-
sone, and cytosine arabinoside. She was discharged
for home care 5 days later. She was continued on
prednisone and allopurinol at home. She received
additional chemotherapy 1 month later (11/1)
and again on 11/14. On 12/6, she was readmitted
because she had painful sores in her mouth and was
unable to eat.
Transcribed Image Text:CASE STUDY 12-2 A 3-year-old girl was admitted with a diagnosis of acute lymphocytic leukemia. Her admitting labora- tory data are shown in Case Study Table 12-2.1. After admission, she was treated by administration of packed red cells, 2 units of platelets, IV fluids, and allopurinol. On the second hospital day, chemother- apy was begun, using IV vincristine and prednisone and intrathecal injections of methotrexate, predni- sone, and cytosine arabinoside. She was discharged for home care 5 days later. She was continued on prednisone and allopurinol at home. She received additional chemotherapy 1 month later (11/1) and again on 11/14. On 12/6, she was readmitted because she had painful sores in her mouth and was unable to eat.
CASE STUDY TABLE 12-2.1
LABORATORY RESULTS
10/1 10/2 10/3 10/4 11/14 12/6 6/20
Urea N
(mg/dL)
12.0
a
a
15
4.0
2.0
Creatinine
(mg/dL)
0.7
a
a
1.0
0.7
a
0.7
Uric acid
(mg/dL)
12.0 9.2 4.0 1.9
2.3
3.1
a
WBC
(mm?)
56,300 a
a 3,700 2,800 3,700
a
"Indicates test not performed.
Transcribed Image Text:CASE STUDY TABLE 12-2.1 LABORATORY RESULTS 10/1 10/2 10/3 10/4 11/14 12/6 6/20 Urea N (mg/dL) 12.0 a a 15 4.0 2.0 Creatinine (mg/dL) 0.7 a a 1.0 0.7 a 0.7 Uric acid (mg/dL) 12.0 9.2 4.0 1.9 2.3 3.1 a WBC (mm?) 56,300 a a 3,700 2,800 3,700 a "Indicates test not performed.
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