**Question:**How will increasing the particle size of the column packing in an HPLC column affect the terms of the van Deemter equation?**Answer Options:**- A. A, B, and C are increased.- B. A is increased; C is decreased; B is unchanged.- C. B and A are increased; C is decreased.- D. B is unchanged; A and C are increased.- E. A is increased; B and C are unchanged.**Explanation:**In High-Performance Liquid Chromatography (HPLC), the van Deemter equation is used to describe the different factors affecting the efficiency of a chromatographic column. The terms A, B, and C in the equation represent different sources of band broadening: - A: Eddy diffusion- B: Longitudinal diffusion- C: Mass transferIncreasing the particle size in the column packing generally impacts these factors and subsequently affects the separation efficiency of the column.

Answered: Image /qna-images/answer/fe97bf96-1af7-46a4-920b-5e2ca7e37942.jpg

How will increasing the particle size of the column packing in an HPLC column affect the terms of the van Deemter equation? A, B, and C are increased. A is increased; C is decreased; B is unchanged. B and A are increased; C is decreased. B is unchanged; A and C are increased. O A is increased; B and C are unchanged.

How will increasing the particle size of the column packing in an HPLC column affect the terms of the van Deemter equation? A, B, and C are increased. A is increased; C is decreased; B is unchanged. B and A are increased; C is decreased. B is unchanged; A and C are increased. O A is increased; B and C are unchanged.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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