How the activity of serotonin and norepinephrine lead to mania?
How the activity of serotonin and norepinephrine lead to mania?
Mania refers to a psychological disorder characterized by extremely excitable and elevated mood. It causes an individual to experience intense mood, unreasonable excitement, hyperactivity, delusions, etc. Mania is a common symptom of type 1 bipolar disorder and can last for one week or more. The symptoms of mania are decreased need for sleep, increase sexual desire, hyperactivity, delusions, rapid speech, increased irritability, and aggression, etc.
Serotonin is a neurotransmitter that is responsible for sending messages between nerve cells. It facilitates the communication between the cells of the brain and other neuron cells. It plays an important role in emotions, appetite, mood, digestion, and sleep. As melatonin's precursor, serotonin helps in the regulation of the body clock and seep-ake cycles. It decreases the ability of activation of excitatory systems due to sexual cues and acts as an inhibitory modulator of sexual desire.
An abnormal increase in the level of serotonin results in a decreased need for sleep, elevated mood and behavior, increased sexual desire, and aggressive behavior, leading to mania.
Norepinephrine is a neurotransmitter that plays a role in concentration, mood, and providing energy to the body by breaking uo fats. The norepinephrine hormone plays a significant role in reaction time, arousal and alertness.
An abnormal increase in norepinephrine level results in euphoria, an increase in hostility and irritable mood, hyperactivity, delusions, leading to Mania.
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