How many extra hydrogen bonds would be needed to hold A and B together at this lower concentration (1 nM each) so that a similar proportion of the molecules are found in the AB complex? (Remember that each hydrogen bond contributes about 1 kcal/mole.)

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How many extra hydrogen bonds would be needed to hold A and B together at this
lower concentration (1 nM each) so that
a similar proportion of the molecules are found in the AB complex? (Remember that
each hydrogen bond contributes about 1 kcal/mole.)
When Ka=10 --> AG° = -8.6 kcal/mole
When Ka = 10° .--> AG° = -12.9 kcal/mole
O 4-5
O 20
40
O 100
Transcribed Image Text:How many extra hydrogen bonds would be needed to hold A and B together at this lower concentration (1 nM each) so that a similar proportion of the molecules are found in the AB complex? (Remember that each hydrogen bond contributes about 1 kcal/mole.) When Ka=10 --> AG° = -8.6 kcal/mole When Ka = 10° .--> AG° = -12.9 kcal/mole O 4-5 O 20 40 O 100
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