How does sickle cell anemia work?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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How does sickle cell anemia work?

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Sickle cell anemia:

 

Sickle cell anemia is a genetic disorder of red blood cells. In this disorder, red blood cells change their shape into a sickle shape. It is a set of a condition like sickle cell crisis, vaso-occlusive crisis, splenic sequestration crisis, and other conditions. At a molecular level, it is a point mutation that leads to defects of red blood cells and this mutation is due to the presence of thymine in DNA strands instead of adenine which later on translates different proteins by the codon.

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