How does pyruvate carboxylase deficiency result in lactic aciduria, an illness in which lactate appears in the urine?

Q: What is the function of the kinase associated with the pyruvate dehydrogenase complex?

A: Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into…

Q: How are the irreversible reactions of glycolysis bypassed in gluconeogenesis?

A: Introduction: Gluconeogenesis is a metabolic pathway where glucose is synthesized from…

Q: Which steps of aerobic metabolism of pyruvate through the citric acid cycle are control points?

A: Cellular respiration can be defined as the series of metabolic reactions that occur in the living…

Q: Where does Gluconeogenesis occur and from what precursors?

A: Gluconeogenesis is the pathway of synthesis of glucose. Gluconeogenesis supplies the needs for…

Q: hat is the main purpose of gluconeogenesis and what triggers it to process

A: The linked series of chemical reactions occurring within a cell constitutes the metabolic pathways.…

Q: Why do deficiencies in glucose 6-phosphate dehydrogenase frequently present as anemia?

A: Glucose 6-phosphate (G6P) deficiency is a genetic abnormality that results in an inadequate amount…

Q: What are the three fates of the pyruvate and list which one is aerobic or anaerobic

A: Glucose is converted into pyruvate through the process of glycolysis. Since pyruvate is the major…

Q: Why does pyruvate either form acoa or lactate? What are the conditions

A: The conversion of pyruvate depends on oxygen availability:1) Aerobic Conditions (With Oxygen):…

Q: What are the structural differences between pyruvate and lactate ions?

A: Pyruvate is the end product of aerobic glycolysis while lactate is the end product of anaerobic…

Q: What is the rule of 2 for gluconeogenesis ?

A: Gluconeogenesis is the process of formation of glucose from glucogenic amino acids. Enzymes involved…

Q: Why is glucose provided by glycogenolysis in the liver but not in skeletal muscle?

A: Through glycogenolysis process, glycogen broken down into glucose and provide energy.  Muscle…

Q: What is the function of the glucose-alanine cycle in normalmetabolism?

A: The glucose-alanine cycle is also known as the alanine cycle or the Cahill cycle. It occurs under…

Q: Under what circumstances would lactate production be increased above normal?

A: Lactate is an organic molecule which is formed maximum in muscle cells.

Q: source regulated? What would you expect to be the effect of caffeine or theophylline on fatty acid…

A: Fatty acids are the main source of energy production because they provide the maximum energy per…

Q: What enzymes outside of the citric acid cycle affect itsregulation?

A: Citric acid cycle is also known as the tricarboxylic acid [TCA] cycle and Krebs cycle. The pyruvic…

Q: What effect does a higher ADP/ATP ratio have on isocitrate dehydrogenase activity?

A: Isocitrate dehydrogenase is an enzyme that catalyzes isocitrate's oxidative decarboxylation,…

Q: With respect to glycogen, what is the likely fate of excess glucose 6-phosphate in muscle?

A: The process of glycolysis in which the glucose is converted to two molecules of pyruvate along with…

Q: Please explain gluconeogenesis. What is it? Where does it occur and why?

A: Gluconeogenesis is a very crucial process in organisms. It plays a vital role in providing energy to…

Q: Which glycogen storage disorder is known as amylopectinosis? explain very briefly.

A: In glycogen storage disease abnormal accumulation of sugar occur in the body due to defective…

Q: What is the function of ATP in the conversion of glutamate to glutamine?

A: Glutamine synthetase is an enzyme which is responsible for metabolism of nitrogen by catalyzing the…

Q: Why is it advantageous that breakdown of glycogen gives rise to glucose-6-phosphate rather than to…

A: Introduction The phosphorolytic cleavage of glycogen results in the formation of glucose-6-phosphate…

Q: What is a common source of pyruvate?

A: Introduction: With a carboxylic acid and a ketone functional group, pyruvic acid (CH3COCOOH) is the…

Q: Pyruvate has three different fates. What are the three different molecules pyruvate is converted…

A: Pyruvate is majorly released from the process of glycolysis, which is a three-carbon compound.

Q: The disease beriberi, which results from a dietary deficiency of vitamin B1 (thiamine), is…

A: Macronutrients and micronutrients are two different types of nutrition. Macronutrients include the…

Q: What are the substrates for gluconeogenesis? What role do fatty acids play ingluconeogenesis?

A: Gluconeogenesis is the metabolic pathway that results in the generation of glucose from certain…

Q: Pyruvate dehydrogenase deficiency, a severe condition with a poor prognosis, results in neurological…

A: BASIC INFORMATION  DISEASE It is basically the illness of the body. This affects our bodily…

Q: What is the fate of the nitrogen on the newly formed glutamate?

A: Amino acid degradation takes place in tissues other than the liver where the first step of…

Q: What is the role of pyruvate dehydrogenase and what are its products?

A: Introduction:- Pyruvate dehydrogenase is an enzyme that catalyzes the reaction of pyruvate and a…

Q: How does the conversion of pyruvate to lactate take place in muscle?

A: Introduction: Pyruvate formed at the end of glycolysis is reduced to lactic acid under anaerobic…