How does non homologous end joining work?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter4: Basic Immunology And Immunohematology
Section4.6: Abo Grouping
Problem 6RQ
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How does non homologous end joining work?

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Step 1

Double-stranded DNA breaks are repaired by several mechanisms. These repair pathways join the broken DNA ends to mend it. These pathways include homologous recombination repair and nonhomologous end-joining. 

 

Step 2

The non-homologous DNA end-joining pathway does not include the homologous sequences of DNA during the process of repair. The pathway becomes activated in the G1 phase of the interphase before the process of DNA replication starts in the S phase. 

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