Homework Problems #2 1. Draw the peptide KTQHV, write the sequence using 3-letter abbreviation for the amino acids, and identify: a. The N- and C-termini. b. Every a-carbon of the sequence, by labeling them with "a". c. All peptide bonds. d. Hydrogen bond donors and acceptors in the polar side chains. e. Covalent bonds that correspond to the backbone phi (D) and psi (4) angles f. Ionizable R-groups of amino acids in this sequence (circle them). i. Choose one ionizable group and draw it at pH 1, pH 7, and pH 14 and indicate the approximate net charge at each pH. ii. What fraction of His residues are charged at pH=5.8?

Homework Problems #2 1. Draw the peptide KTQHV, write the sequence using 3-letter abbreviation for the amino acids, and identify: a. The N- and C-termini. b. Every a-carbon of the sequence, by labeling them with "a". c. All peptide bonds. d. Hydrogen bond donors and acceptors in the polar side chains. e. Covalent bonds that correspond to the backbone phi (D) and psi (4) angles f. Ionizable R-groups of amino acids in this sequence (circle them). i. Choose one ionizable group and draw it at pH 1, pH 7, and pH 14 and indicate the approximate net charge at each pH. ii. What fraction of His residues are charged at pH=5.8?

Biochemistry

9th Edition

ISBN:9781305961135

Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Publisher:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Chapter3: Amino Acids And Peptides

Section: Chapter Questions

Problem 10RE: MATHEMATICAL Calculate the isoelectric point of each of the following amino acids: glutamic acid,...

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