HO. но HO several steps I2 NaHCO, но OCH3 Но Он но iodolactonization OCH3 PGF24

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Lactones, cyclic esters such as compound A, are prepared by halolactonization, an addition reaction to an alkene. For example, iodolactonization of B forms lactone C, a key intermediate in the synthesis of prostaglandin PGF2α (Section 4.15). Draw a stepwise mechanism for this addition reaction.

HO.
но
HO
several steps
I2
NaHCO,
но
OCH3
Но
Он
но
iodolactonization
OCH3
PGF24
Transcribed Image Text:HO. но HO several steps I2 NaHCO, но OCH3 Но Он но iodolactonization OCH3 PGF24
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