HIN 2-Dietnyiul Show how this compound can be prepared from ethylene (2) oxide and diethylamine. 10.42 Following is a two-step synthesis of the antihyperten- sive drug propranolol, a so-called beta blocker with vasodilating action: -CH3 OH K9CO3 Cl + (1) 1-Naphthol Epichlorohydrin is one f pro- hetics. chetics (2) , and c acid (See N. (2) DH Propranolol (Cardinol) Propranolol and other beta blockers have received enormous clinical attention
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
I have this task in organic chemistry (book: Brown's introduction to organic chemisty, global edition). Task 10:42.
In (a) I have to tell what the funcion of K2CO3 is in step 1. Is it that CO32- take the hydrogen atom in 1-napthol? Will it then be a SN2 mechanism?
In (b) I have to name the
Here are two pictures of the task:
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
