Here is my question for you: Protein called p53 is known to have a very important function is cell life and death. There is a gene called p53 that codes for this protein. When the time comes for an old cell to die, this gene gets turned on. It gets transcribed into p53 mRNA, then this mRNA gets translated by ribosomes into the p53 protein, which then gets activated. Once activated, p53 Protein initiates the self-destruction of the old cell. The process of programmed self-destruction of cells is called Apoptosis. Recently, scientists discovered that in cancer cells, the gene coding for p53 protein is mutant (wrong DNA sequence). Step by step describe the consequences of p53 gene mutation: Describe starting from transcription, to translation, to activation, ending with function, how this protein's shape (and function) could come out different/abnormal, after a change in p53 DNA sequence. How can it lead to development of masses of cells (tumors)?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Here is my question for you:
Protein called p53 is known to have a very important function is cell life and death.
There is a gene called p53 that codes for this protein. When the time comes for an old cell to die, this gene gets turned on. It gets
transcribed into p53 mRNA, then this mRNA gets translated by ribosomes into the p53 protein, which then gets activated. Once
activated, p53 Protein initiates the self-destruction of the old cell. The process of programmed self-destruction of cells is called
Apoptosis. Recently, scientists discovered that in cancer cells, the gene coding for p53 protein is mutant (wrong DNA sequence).
Step by step describe the consequences of p53 gene mutation: Describe starting from transcription, to translation, to activation,
ending with function, how this protein's shape (and function) could come out different/abnormal, after a change in p53 DNA
sequence. How can it lead to development of masses of cells (tumors)?
ના * 252 tumor Gumpressor inclure the Immo
weatively requilate
Transcribed Image Text:Here is my question for you: Protein called p53 is known to have a very important function is cell life and death. There is a gene called p53 that codes for this protein. When the time comes for an old cell to die, this gene gets turned on. It gets transcribed into p53 mRNA, then this mRNA gets translated by ribosomes into the p53 protein, which then gets activated. Once activated, p53 Protein initiates the self-destruction of the old cell. The process of programmed self-destruction of cells is called Apoptosis. Recently, scientists discovered that in cancer cells, the gene coding for p53 protein is mutant (wrong DNA sequence). Step by step describe the consequences of p53 gene mutation: Describe starting from transcription, to translation, to activation, ending with function, how this protein's shape (and function) could come out different/abnormal, after a change in p53 DNA sequence. How can it lead to development of masses of cells (tumors)? ના * 252 tumor Gumpressor inclure the Immo weatively requilate
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