Helium gas is maintained at a partial pressure in alveolar gas of PHe,alv= 10 mmHg. Blood flow through the lungs is 5 L/min, the permeability surface area of the alveolar blood-gas barrier is PHe,M S= 100 L.Lil:L.
Helium gas is maintained at a partial pressure in alveolar gas of PHe,alv= 10 mmHg. Blood flow through the lungs is 5 L/min, the permeability surface area of the alveolar blood-gas barrier is PHe,M S= 100 L.Lil:L.
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Transcribed Image Text:Helium gas is maintained at a partial
pressure in alveolar gas of PHe,alv= 10
mmHg. Blood flow through the lungs is 5
L/min, the permeability surface area of the
alveolar blood-gas barrier is PHe,M S= 100
mL/s, and Bunsen solubility coefficients for
He in blood and barrier are a*He,blood=
0.008 mL He/(mL blood* atm) and
a*He,M= 0.08 mL He/(ml blood* atm),
respectively. Helium is not present in the
inlet blood.
Find the He flow across the microvascular
barrier of the lung.
Compare this with the maximum helium
exchange for very high flow rates (diffusion
limited).
Compare the result in part (a) with the He flow
when the permeability is very high (flow-
limited).
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