(Hardy-Weinberg.) Suppose that a particular gene occurs as one of two alleles (A and a), where allele A has frequency 0 € (0, 1) in the population. That is, a random copy of the gene is A with probability and a with probability 1-0. Since a diploid genotype consists of two genes, the probability of each genotype is given by: genotype AA Aa aa probability ² 20(1 – 0) (1 – 0)² Suppose we test a random sample of people and find that n₁ are AA, n₂ are Aa, and n are aa. Find the maximum likelihood estimator ên. Make sure to verify that it is indeed maximizing, by computing the second derivative of the function you are maximizing.
(Hardy-Weinberg.) Suppose that a particular gene occurs as one of two alleles (A and a), where allele A has frequency 0 € (0, 1) in the population. That is, a random copy of the gene is A with probability and a with probability 1-0. Since a diploid genotype consists of two genes, the probability of each genotype is given by: genotype AA Aa aa probability ² 20(1 – 0) (1 – 0)² Suppose we test a random sample of people and find that n₁ are AA, n₂ are Aa, and n are aa. Find the maximum likelihood estimator ên. Make sure to verify that it is indeed maximizing, by computing the second derivative of the function you are maximizing.
A First Course in Probability (10th Edition)
10th Edition
ISBN:9780134753119
Author:Sheldon Ross
Publisher:Sheldon Ross
Chapter1: Combinatorial Analysis
Section: Chapter Questions
Problem 1.1P: a. How many different 7-place license plates are possible if the first 2 places are for letters and...
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