Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
give transformation
![OEt
Et,NH (1 equiv) / pyridine
CI](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F14494f59-88ab-4e14-bfe6-eddafc8b6be3%2F93460ff0-b178-49c0-a3d6-26ee5598a62f%2Fg950ii_processed.png&w=3840&q=75)
Transcribed Image Text:OEt
Et,NH (1 equiv) / pyridine
CI
Expert Solution
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Step 1
Diethyl amine can behave as a nucleophile with carbonyl compounds.
Step 2
In the given substrate, there are two carbonyl groups. The lone pair of electrons on the nitrogen atom of Et2NH attacks the electrophilic carbonyl carbon. In the given molecule, the carbonyl carbon substituted with –Cl is more electrophilic than the other carbonyl group as –OEt is electron-donating. Pyridine acts as a base in this reaction. It abstracts the acidic proton from the ammonium intermediate.
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