Give the product(s) and show step by step reaction mechanism (s) for the following reactions. Give an energy diagram for each transformation. If rhe reaction mechanism has a specific technical term describe it. 1) sodium methoxide + tert- butylbromide 2) potassium tert-butoxide + methylbromide 3) mixture of cyclohexene, chloroform and 50% KOH solution 4) cyclohexylbromide + ethanol

Heck reactions take place with alkynes as well as alkenes. The following conversion involves an intramolecular Heck reaction followed by an intermolecular Heck. Work out the reaction sequence on a separate sheet of paper, and then draw the structure of the palladium-containing intermediate A. 1% mol Pd(OAc)₂2 CO₂Me 4% mol Ph P CH₂CN A (1 ring) C (2 rings) (2 rings) • Consider E/Z stereochemistry of alkenes. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. • Use R1 to represent the palladium complex. The R group tool is located in the charges and lone pairs drop-down menu. 0- ✪ Sn [F MeO₂C

The following transformation can be accomplished by using to make the product. 1) Br2, FeBr3 2) HBr, 40 °C 3) Cl2, FeCl3 X 4) SO3 H2SO4 CH3 TABLE OF REAGENTS 7) CH3CH₂CH2CH2C1, AICI3 8) HNO3, H2SO4 9) CH₂CHCHCH2, heat 5) C6H5MgBr, Ether 6) CH3CH2CH2COCI, AICI3 to make compound X followed by 10) NBS, CCI4, peroxide 11) (CH3)2CHOH, H₂SO4 12) Zn (Hg) HCI -

In each reaction box, place the best reagent and conditions from the list below он ... он 2) 3) HаCrOд Н2О2, NaOH, H20 Br2 Cl2, H20 PCI3 ВН- THF H2SO4 (conc.) dilute H3O* NaBH4 in EtOH

Carry out the following reactions by showing the step by step transformation. More than one step may be required.

please step by step solution.

Bromo compound N can undergo substitution with nucleophiles X to give mixtures of products O and P as shown below. Explain how this is possible, and suggest an explanation for the observation that the proportion of product P increases with increasing solvent polarity. F N Br X- O X ...X F P

Give detailed Solution with explanation

Please could someone with Chemdraw software create the mechanism for wittig reaction with these reagents. Thank you

Give the reagents necessary for the synthesis above and please show the detailed step-by-step mechanism.