Give the ABBREVIATED NAME of the nucleotide in the 5' end. "Oe-OCH,95 pmP Type here to search40 ENG05/11/2021 3. What type of nucleic acid does this chain of nucleotides occur? Provide the complete name using CAPITAL LETTERS. Do NOT givethe abbreviated name. *O OCH,Ow-OCH,-OCH93 pmP Type here to searchAD 40 ENGs/11/2021

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Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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What will be the order of amino acids derived from the following DNA sequence 5’-TGATCGCACAAT-3’? Explain briefly. (1.5) If the base G (denoted by an asterisk) in the sequence 5’-TGATCG*CACAAT-3’ is replaced by C due to a mutation, the new sequence will be 5’-TGATCCCACAAT-3’ what will be the new amino acid sequence? Explain briefly. (1.5) If the anticodon sequence of a tRNA is 5’-GCG-3’, what amino acid will it carry? Explain briefly. (1.5) What would be the effect of mutation if the C is changed to A in the anticodon? Explain briefly. (1.5)
Draw the structure of a G ∙ U base pair.
What is the difference between the 3′ end and the 5′ end of a polynucleotide?
draw a strand of DNA 4 nucleotides long (4 nucleotides on each side). Label the 5’ ends, the 3’ ends, the bond that holds the DNA backbone together, the glycosyl bond, and the bond that holds the nitrogenous bases together. You can use “P” to represent phosphate, and ATCG to represent the nitrogenous bases. Please try to draw the sugar accurately and include any unbonded functional groups, including the oxygen within the molecule.
You have to label the numbers. Then the last two parts are just names.
Consider a three-base sequence in the template of DNA: 5' . . . 123 . . .3', in which 1, 2, and 3 refer to the relative positions of deoxyribonucleotides.Comment on the probable effect on the resulting protein if the following point mutations (one-base substitutions) occurred.(a) changing one purine for another in position 1(b) changing one pyrimidine for another in position 2(c) changing a purine to a pyrimidine in position 2(d) changing one purine for another in position 3
5'-GCGGTACGTTACGGCTTTACTGACCTGCAGGC-3' A. Convert this to a double strand DNA molecule by writing the complementary sequence. Be sure to correctly label the ends of the double stranded molecule B. Pick one of the two strands and write the sequence of an RNA molecule that could be transcribed from it. Again, you must correctly label the ends of the molecule.
In a segment of DNA consisting of 1000 nitrogen bases, 28% of which are thymine, how many bases are adenine, guanine, and cytosine?
Where is the substitution indicated on the original DNA strand? May you please Write it out and bold the nucleotide.
Explain why indels that involve just one or two nucleotides have more severe consequences than indels that involve three contiguous nucleotides.
Using Chargaff’s rule of base pairing determine the amount of guanine in 120 bp long fragment of double strand DNA if there are 45 adenines present. Show your work for credit.
In the DNA double-helix structure, the larger of the two grooves formed by the helical twist where certain base pairs are exposed is called the:

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Give the ABBREVIATED NAME of the nucleotide in the 5' end." OCH