Geometric isomerism in cyclic compounds also has significant implications for the compound's reactivity and interactions with biological systems. The specific arrangement of substituents can influence the molecule's ability to fit into enzyme active sites or interact with receptors, leading to different biological activities. For example, certain cyclic compounds with medicinal properties can exhibit different therapeutic effects depending on whether they are in the cis or trans configuration. This is particularly important in drug design, where the efficacy and safety of a drug can be heavily influenced by its geometric isomerism.
Geometric isomerism in cyclic compounds also has significant implications for the compound's reactivity and interactions with biological systems. The specific arrangement of substituents can influence the molecule's ability to fit into enzyme active sites or interact with receptors, leading to different biological activities. For example, certain cyclic compounds with medicinal properties can exhibit different therapeutic effects depending on whether they are in the cis or trans configuration. This is particularly important in drug design, where the efficacy and safety of a drug can be heavily influenced by its geometric isomerism.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Geometric isomerism in cyclic compounds also has significant implications for the compound's reactivity and interactions
with biological systems. The specific arrangement of substituents can influence the molecule's ability to fit into enzyme
active sites or interact with receptors, leading to different biological activities. For example, certain cyclic compounds with
medicinal properties can exhibit different therapeutic effects depending on whether they are in the cis or trans
configuration. This is particularly important in drug design, where the efficacy and safety of a drug can be heavily
influenced by its geometric isomerism.
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