Genetic linkage between alleles can modify how natural selection affects the frequencies of neutral, deleterious, and beneficial alleles. In the follow scenarios, you will consider the fates of alleles at two loci (A and B) under different amounts of genetic linkage. Write 1-2 sentences explaining what you expect to happen under the following scenarios, and why you expect it. A. Assume that there are two neutral alleles at the B locus (B and b). A beneficial mutation arises in the A locus (A) on a haplotype where it is linked to the ballele. Assuming tight genetic linkage between A' and b (c≈ 0), what do you expect to happen to the frequency of the ballele and why? B. Assume there is a deleterious allele at the B locus (b) and a beneficial allele (B). A beneficial mutation arises in the A locus (A) on a haplotype where it is linked to the b allele. The benefit of the A' allele is greater than the deleterious effect of the b allele, and there is tight genetic linkage between A' and b (c≈ 0). What do you expect to happen to the frequency of the ballele and why? C. Assume there is a deleterious allele at the B locus (b) and a beneficial allele (B). A beneficial mutation arises in the A locus (A) on a haplotype where it is linked to the b allele. The benefit of the A' allele is greater than the deleterious effect of the b allele, and there is substantial recombination between A' and b (c> 0). What do you expect to happen to the frequency of the ballele and why? D. Assume there is a deleterious allele at the B locus (b) and a beneficial allele (B). A deleterious mutation arises in the A locus (A") on a haplotype where it is linked to the B allele. The cost of the A" allele is less than the beneficial effect of the B allele, and there is tight genetic linkage between A and B (c≈ 0). What do you expect to happen to the frequency of the A and B alleles and why?
Evolutionary Genetics
Evolution is known as continuous changes that occur to adjust organisms in their changing environment over many generations. Various theories have been proposed to illustrate the origin of life and organic evolution. The most accepted one is the theory of natural selection by Charles Darwin. According to his postulate, organisms undergo a struggle for existence due to overproduction. To survive in nature, they acquire variations. The inheritable variations are selected by nature, and it leads to the survival of the fittest.
Phenotype Frequency
The majority of populations have a certain degree of variation in their genetic pools. Scientists can predict the genetic variation happening over time by measuring the amount of genetic variation in a population and these predictions assist them in gaining important insights into the processes that allow organisms to adapt to the environment or to develop into new species over generations. This process is referred to as the process of evolution.
Hardy Weinberg Equilibrium
The frequencies of allele and genotype were maintained constant from one generation to another due to the absence of other evolutionary forces. It is otherwise called the Hardy Weinberg principle the field of population genetics.
please help with a, b, c, and d all of them asap!
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