Gastric juice is made up of substances secreted from parietal cells, chief cells, and mucous-secreting cells. The cells secrete HCl, proteolytic enzyme zymogens, mucin, and intrinsic factor. The pH of gastric juice is acidic, between 1–3. If the pH of gastric juice is 1.9, what is the amount of energy (AG) required for the transport of hydrogen ions from a cell (internal pH of 7.4) into the stomach lumen? Assume that the potential difference across the membrane separating the cell and the interior of the stomach is –70.0 mV (inside of the cell is negative relative to the lumen of the stomach). Assume that the temperature is 37 °C. The Faraday constant is 96.5 kJ/(V•mol) and the gas constant is 8.314 x 10-3 kJ/(mol·K).

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Gastric juice is made up of substances secreted from parietal cells, chief cells, and mucous-secreting cells. The cells secrete
HCI, proteolytic enzyme zymogens, mucin, and intrinsic factor. The pH of gastric juice is acidic, between 1–3.
If the pH of gastric juice is 1.9, what is the amount of energy (AG) required for the transport of hydrogen ions from a cell
(internal pH of 7.4) into the stomach lumen? Assume that the potential difference across the membrane separating the cell
and the interior of the stomach is –70.0 mV (inside of the cell is negative relative to the lumen of the stomach). Assume
that the temperature is 37 °C.
The Faraday constant is 96.5 kJ/(V-mol) and the gas constant is 8.314 x 10-3 kJ/(mol·K).
Express your answer in kilojoules per mole.
A =
10.68
kJ/mol
Transcribed Image Text:Gastric juice is made up of substances secreted from parietal cells, chief cells, and mucous-secreting cells. The cells secrete HCI, proteolytic enzyme zymogens, mucin, and intrinsic factor. The pH of gastric juice is acidic, between 1–3. If the pH of gastric juice is 1.9, what is the amount of energy (AG) required for the transport of hydrogen ions from a cell (internal pH of 7.4) into the stomach lumen? Assume that the potential difference across the membrane separating the cell and the interior of the stomach is –70.0 mV (inside of the cell is negative relative to the lumen of the stomach). Assume that the temperature is 37 °C. The Faraday constant is 96.5 kJ/(V-mol) and the gas constant is 8.314 x 10-3 kJ/(mol·K). Express your answer in kilojoules per mole. A = 10.68 kJ/mol
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