Frog muscle cells and the solution bathing the cells contain ions at different concentrations. The concentrations of Na+, Ca²+, K+ and Cl¯ are shown in the table. The temperature is 25 °C. ion intracellular concentration (mm) Na+ 12 extracellular concentration 120 Ca²+ 1 x 10-4 3 K+ 155 10 CI- 4 62 (MM) The resting frog muscle membrane potential is determined by the equilibrium of K+ across the cell membrane. What is the voltage inside the frog cell if the outside solution is at zero volts?

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Frog muscle cells and the solution bathing the cells contain ions at different concentrations. The concentrations of Na⁺, Ca²⁺, K⁺, and Cl⁻ are shown in the table. The temperature is 25 °C.

| Ion | Na⁺ | Ca²⁺ | K⁺ | Cl⁻ |
|-----|-----|-----|-----|-----|
| **Intracellular concentration (mM)** | 12 | 1 × 10⁻⁴ | 155 | 4 |
| **Extracellular concentration (mM)** | 120 | 3 | 10 | 62 |

The resting frog muscle membrane potential is determined by the equilibrium of K⁺ across the cell membrane. What is the voltage inside the frog cell if the outside solution is at zero volts?
Transcribed Image Text:Frog muscle cells and the solution bathing the cells contain ions at different concentrations. The concentrations of Na⁺, Ca²⁺, K⁺, and Cl⁻ are shown in the table. The temperature is 25 °C. | Ion | Na⁺ | Ca²⁺ | K⁺ | Cl⁻ | |-----|-----|-----|-----|-----| | **Intracellular concentration (mM)** | 12 | 1 × 10⁻⁴ | 155 | 4 | | **Extracellular concentration (mM)** | 120 | 3 | 10 | 62 | The resting frog muscle membrane potential is determined by the equilibrium of K⁺ across the cell membrane. What is the voltage inside the frog cell if the outside solution is at zero volts?
Expert Solution
Step 1: Given,

The concentrations of Na+, Ca2+, K+, and Cl- are shown in the following table. 

Temperature = 25 °C

IONNa+Ca2+K+Cl-
intracellular concentration (mM)121 X 10-41554
extracellular concentration (mM)12031062

The resting frog muscle membrane potential is determined by the equilibrium of K+ across
the cell membrane. 

We have to find the voltage inside the frog cell if the outside solution is at zero volts.

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