Frederick Griffith conducted an experiment using 2 different strains of the bacterium Streptococcus pneumoniae. As you can see in the diagram below, the S strain bacteria killed the mice and the R strain bacteria did not kill the mice. What is the difference in structure between the S and R strains? Why does the dead mouse contain living S strain when only dead S strain was injected?

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Nitrogeneous base.
III. Frederick Griffith (Early 1930s)
Frederick Griffith conducted an experiment using 2 different strains of the bacterium Streptococcus pneumoniae. As you can see in
the diagram below, the S strain bacteria killed the mice and the R strain bacteria did not kill the mice. What is the difference in
structure between the S and R strains? Why does the dead mouse contain living S strain when only dead S strain was
injected?
EXPERIMENT
Living S cells
(control)
Heat-killed
S cells
(control)
Mixture of
heat-killed
S cells and
living R cells
Living R cells
(control)
S Strain = pathogenic/virulent
R Strain = non pathogenic
00
80
RESULTS
Mouse dies
Mouse healthy Mouse healthy Mouse dies
Living S cells
Transcribed Image Text:Nitrogeneous base. III. Frederick Griffith (Early 1930s) Frederick Griffith conducted an experiment using 2 different strains of the bacterium Streptococcus pneumoniae. As you can see in the diagram below, the S strain bacteria killed the mice and the R strain bacteria did not kill the mice. What is the difference in structure between the S and R strains? Why does the dead mouse contain living S strain when only dead S strain was injected? EXPERIMENT Living S cells (control) Heat-killed S cells (control) Mixture of heat-killed S cells and living R cells Living R cells (control) S Strain = pathogenic/virulent R Strain = non pathogenic 00 80 RESULTS Mouse dies Mouse healthy Mouse healthy Mouse dies Living S cells
Expert Solution
Step 1

Frederick Griffith performed an experiment using two different Strains of bacteria. The S strain was virulent and resulted in the death while R strain was nin virulent which remained the mouse as healthy. 

When the S strain was killed and inserted along with the live R strain bacteria it resulted in the death of mouse. This was due to the structure difference in both the microbes. 

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