Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene. This gene is expressed at a different level in different tissue types. Using a sequencing method called "RNAseq," a researcher determines the level of FOXP2 expression in 10 different samples of lung tissue, and obtains these data: 1154 5998 1007 2501 1000 988 2547 3987 4187 887 The scientist has previously determined that FOXP2 is expressed in brain tissue at a level of 6,537. Calculate the Z- score associated with a test to see if the average expression of FOXP in her lung tissue samples is different from the levels she measured from brain tissue. • Report your answer to 3 decimal places! • Answers should be positive! • This is technically a two-tailed test We can make the math easier though since Z distributions are symmetrical • A right-tailed Z test with alpha = 0.05 works out the same as doing a two-tailed test with alpha = 0.025 in each tail
Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene. This gene is expressed at a different level in different tissue types. Using a sequencing method called "RNAseq," a researcher determines the level of FOXP2 expression in 10 different samples of lung tissue, and obtains these data: 1154 5998 1007 2501 1000 988 2547 3987 4187 887 The scientist has previously determined that FOXP2 is expressed in brain tissue at a level of 6,537. Calculate the Z- score associated with a test to see if the average expression of FOXP in her lung tissue samples is different from the levels she measured from brain tissue. • Report your answer to 3 decimal places! • Answers should be positive! • This is technically a two-tailed test We can make the math easier though since Z distributions are symmetrical • A right-tailed Z test with alpha = 0.05 works out the same as doing a two-tailed test with alpha = 0.025 in each tail
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:### Expression of FOXP2 Gene in Lung Tissue Samples
Forkhead box protein P2 (FOXP2) is a protein encoded by the FOXP2 gene in humans. The expression of this gene varies across different tissue types. Using a sequencing technique known as "RNAseq," a researcher measured FOXP2 expression levels in 10 lung tissue samples, yielding the following data:
- 1154
- 5998
- 1007
- 2501
- 1000
- 988
- 2547
- 3987
- 4187
- 887
### Research Analysis
The researcher had previously identified that FOXP2 expression in brain tissue is at a level of 6,537. The task is to calculate the Z-score to determine if the average expression of FOXP2 in lung tissue samples differs from the brain tissue level.
### Instructions for Calculation
- **Report your answer to 3 decimal places!**
- **Answers should be positive!**
- Note that this is technically a two-tailed test.
- Since Z distributions are symmetrical, calculations can be simplified.
- A right-tailed Z test with alpha = 0.05 is equivalent to a two-tailed test with alpha = 0.025 in each tail.
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