For the past several months, a 24-year-old male has experienced fatigue, puffiness, and overall weakness. One day he noticed his urine had a red to brown discoloration, and that his urine volume was minimal. He went to the emergency room, where urinalysis, blood work, and other tests were done to obtain the following data:

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Question 1.
For the past several months, a 24-year-old male has experienced fatigue, puffiness, and overall weakness. One day he noticed his urine had a red to brown discoloration, and that his urine volume was minimal. He went to the emergency room, where urinalysis, blood work, and other tests were done to obtain the following data:

### Urinalysis Results
- **Appearance:** Red to brown
- **Specific Gravity:** 1.025
- **Blood:** Positive
- **Glucose:** Negative
- **Protein:** Mild

### Hematology Results
- **Serum Sodium:** 125 mEq/L
- **Serum Potassium:** 6 mEq/L
- **Serum Creatinine:** 2.6 mg/dL
- **BUN:** 24.0 mg/dL
- **pH (arterial):** 7.32
- **Hematocrit:** 25%

### Renal Function Tests
- **GFR (Glomerular Filtration Rate):** 40 mL/min
- **RBF (Renal Blood Flow):** 280 mL/min

### Questions
1. What disorder is affecting this individual? What situation(s) predispose an individual to this disorder?
2. Why is there blood in the urine?
3. How do the renal function tests for this individual compare to a healthy individual?
4. What is causing the patient’s puffy feeling?
Transcribed Image Text:For the past several months, a 24-year-old male has experienced fatigue, puffiness, and overall weakness. One day he noticed his urine had a red to brown discoloration, and that his urine volume was minimal. He went to the emergency room, where urinalysis, blood work, and other tests were done to obtain the following data: ### Urinalysis Results - **Appearance:** Red to brown - **Specific Gravity:** 1.025 - **Blood:** Positive - **Glucose:** Negative - **Protein:** Mild ### Hematology Results - **Serum Sodium:** 125 mEq/L - **Serum Potassium:** 6 mEq/L - **Serum Creatinine:** 2.6 mg/dL - **BUN:** 24.0 mg/dL - **pH (arterial):** 7.32 - **Hematocrit:** 25% ### Renal Function Tests - **GFR (Glomerular Filtration Rate):** 40 mL/min - **RBF (Renal Blood Flow):** 280 mL/min ### Questions 1. What disorder is affecting this individual? What situation(s) predispose an individual to this disorder? 2. Why is there blood in the urine? 3. How do the renal function tests for this individual compare to a healthy individual? 4. What is causing the patient’s puffy feeling?
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