For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged. The carboxylic acid group of alanine has a pK₁ of 3. The amino group of alanine has a pK₁ of 8. Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.
For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged. The carboxylic acid group of alanine has a pK₁ of 3. The amino group of alanine has a pK₁ of 8. Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.
Introduction to General, Organic and Biochemistry
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ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter22: Proteins
Section: Chapter Questions
Problem 22.49P: 22-49 Based on your knowledge of the chemical properties of amino acid side chains, suggest a...
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![For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged
carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group
is charged.
The carboxylic acid group of alanine has a pK₁ of 3. The amino group of alanine has a pK₂ of 8.
Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.
concentration ratio:
Incorrect
X10-3](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F76ee89b8-722d-4c27-b7b7-9a80c7775531%2Ffbb78f77-932a-4ded-a7d9-da25cc2535c7%2Fykljsdl_processed.png&w=3840&q=75)
Transcribed Image Text:For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged
carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group
is charged.
The carboxylic acid group of alanine has a pK₁ of 3. The amino group of alanine has a pK₂ of 8.
Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.
concentration ratio:
Incorrect
X10-3
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