For questions 12-13, refer to the following table. Enzyme carbonic anhydrase fumarase ribonuclease 12. 13. acetylcholinesterase KM (mol/L) 2.6 x 10-2 5 x 10-6 Kcat (S-1) 4 x 105 800 7.9 x 10-3 9.5 x 10-5 790 1.4 x 104 (1 point) Calculate the initial reaction velocity for acetylcholinesterase (corresponding to the initial few percent of substrate consumed). Assume a total enzyme concentration of 1 nM and substrate concentration of 100 mM. Show your work. (1 point) For ribonuclease, what concentration of substrate is needed to produce half the velocity that would be obtained in the limit of an "infinitely high" concentration of substrate?

The following data were obtained in a study of an enzyme known to follow Michaelis-Menten kinetics. Product formed (mmol/min) Substrate added (mmol/L) 217 0.8 325 2 433 4 488 6 647 1000 The Km for this enzyme is approximately: 4 mM. 2 mM. 1 mM. 6 mM. 1000 mM.

The "hill" in the activation profile that reactants must pass over is called the:

Please give me very detailed solution.

1. A daily low dosage of aspirin (acetylsalicylic acid) can lower the risk of heart attack and stroke for individuals at risk. Aspirin suppresses the generation of prostaglandins by irreversible binding to the enzyme COX-1. Inhibition of prostaglandin synthesis lowers the production of thromboxanes that are responsible for the aggregation of platelets and the formation of blood clots. You will explore the mechanism of aspirin binding. 1.1 The average pH of the human body is 7.4 (also known as a physiological pH). Draw the structure of aspirin at a physiological pH. OH 1.2 Aspirin reacts with the amino acid Serine. What is the structure of serine? Draw the structure of the tripeptide Ala-Ser-Trp (draw these structures as they exist at physiological pH) serine Ala-Ser-Trp 1.3 Aspirin reacts with Serine 530 of COX-1 by transesterification reaction. Draw a general mechanism of acid-catalyzed transesterification reaction. Use HA as an acid. 1.4 Draw an arrow-pushing mechanism for the…

Q 25 please

Write the Ksp expression for the sparingly soluble compound calcium phosphate, Ca3(PO4)2- Ksp If either the numerator or denominator is 1, please enter 1.

what is Buffon^ prime Collision Theory?

For the following reaction of protein dimerization, 2P ® P2 the concentration of protein monomer, P, inthe aqueous solution at time zero was 0.2x10-3 mol L-1 and at time 200s the concentration was0.02x10-3 mol L-1. Calculate the reaction rate constant k. Select the closest value.

What is the difference between an activated complex and a transition state?