For each of the following reactions, predict the major product. NaOH H20, A H2 Raney Ni, A, pressure он H,CrO4, H,SO4, H20

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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First 3 major products
**Pre-Class Activity #11**

*Due: 10/30*

For each of the following reactions, predict the major product.

1. **Reaction 1:**
   - Starting Material: A ketone with an aromatic ring.
   - Reagents: NaOH, H₂O, Δ

2. **Reaction 2:**
   - Starting Material: An alkyne with a cyano group.
   - Reagents: H₂, Raney Ni, Δ, pressure

3. **Reaction 3:**
   - Starting Material: A cyclohexanol.
   - Reagents: H₂CrO₄, H₂SO₄, H₂O

---

**Task:**

Propose a forward synthesis for *one* of the two sequences below using whatever reagents necessary. Do not include any curved-arrow mechanisms, just the reactions.

**Sequence 1:**

1. Starting material: An unsaturated ketone.
2. Product: A compound with an extended alkyl chain connected to a phenyl group.

**OR**

**Sequence 2:**

1. Starting material: A hydroxy ketone.
2. Product: An extended chain alcohol.

Consider the appropriate reagents and conditions needed to convert the starting materials to the desired products.
Transcribed Image Text:**Pre-Class Activity #11** *Due: 10/30* For each of the following reactions, predict the major product. 1. **Reaction 1:** - Starting Material: A ketone with an aromatic ring. - Reagents: NaOH, H₂O, Δ 2. **Reaction 2:** - Starting Material: An alkyne with a cyano group. - Reagents: H₂, Raney Ni, Δ, pressure 3. **Reaction 3:** - Starting Material: A cyclohexanol. - Reagents: H₂CrO₄, H₂SO₄, H₂O --- **Task:** Propose a forward synthesis for *one* of the two sequences below using whatever reagents necessary. Do not include any curved-arrow mechanisms, just the reactions. **Sequence 1:** 1. Starting material: An unsaturated ketone. 2. Product: A compound with an extended alkyl chain connected to a phenyl group. **OR** **Sequence 2:** 1. Starting material: A hydroxy ketone. 2. Product: An extended chain alcohol. Consider the appropriate reagents and conditions needed to convert the starting materials to the desired products.
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