Following is an outline of one of the first syntheses of the antidepressant fluoxetine (Prozac). „NMe, Но. NMe, NMe, A B C D. OEt NMeg OE F,C Me CH,ONa FC F&C E F ÇOOH Me `Me F.C F,C An N-substituted Fluoxetine carbamic acid

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Is fluoxetine chiral? If so, which of the possible stereoisomers are formed in this synthesis?

Following is an outline of one of the first syntheses of the antidepressant fluoxetine
(Prozac).
„NMe,
Но.
NMe,
NMe,
A
B
C
D.
OEt
NMeg OE
F,C
Me
CH,ONa
FC
F&C
E
F
ÇOOH
Me
`Me
F.C
F,C
An N-substituted
Fluoxetine
carbamic acid
Transcribed Image Text:Following is an outline of one of the first syntheses of the antidepressant fluoxetine (Prozac). „NMe, Но. NMe, NMe, A B C D. OEt NMeg OE F,C Me CH,ONa FC F&C E F ÇOOH Me `Me F.C F,C An N-substituted Fluoxetine carbamic acid
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