fin Share 1. Standards for Formulating Research Questions RQ-1: Identify gaps in evidence Analysis of gaps in the evidence based on systematic reviews should be used to support the need for a proposed study. If a systematic review is not available, a systematic review should be performed using accepted standards in the field (see standard SR-1), or a strong rationale should be presented for proceeding without a systematic review. In the case where a systematic review is not possible, the methods used to review the literature should be explained and justified.

fin Share 1. Standards for Formulating Research Questions RQ-1: Identify gaps in evidence Analysis of gaps in the evidence based on systematic reviews should be used to support the need for a proposed study. If a systematic review is not available, a systematic review should be performed using accepted standards in the field (see standard SR-1), or a strong rationale should be presented for proceeding without a systematic review. In the case where a systematic review is not possible, the methods used to review the literature should be explained and justified.