**Transcription for Educational Use: Reaction Mechanism Exercise****Problem Statement:**Fill in the boxes with the missing products of each reaction. For box B to C, suggest a mechanism for that reaction step.**Reaction Sequence:**1. Starting Material: Ethyl 6-oxoheptanoate (EtO₂C(CH₂)₅CO₂Et) - Reagent: Sodium ethoxide (NaOEt) in ethanol (EtOH). - Result: Intermediate Product A.2. Intermediate Product A - Reagent: Sodium ethoxide (NaOEt) in ethanol (EtOH) with 1-bromohexane. - Result: Intermediate Product B.3. Intermediate Product B - Conditions: Acidic hydrolysis (H₃O⁺) and heat (Δ). - Result: Final Product C.**Diagram Explanation:**- The reaction starts with an ester compound, where a sodium ethoxide base will generate an enolate. - In step 2, the enolate will react with 1-bromohexane through nucleophilic substitution to yield the alkylated product.- The final step involves acidic hydrolysis and heating to convert the ester into an acid or another desired compound,- Filling in products A, B, and C requires understanding the mechanisms of enolate chemistry and nucleophilic substitution. Suggest a detailed mechanism for creating Product B from A, then for converting B to C under acidic conditions.

Answered: Image /qna-images/answer/654b6f14-b13a-426d-b35d-46dd7db50c4e.jpg

Answered: Fill in the boxes with the missing…

Fill in the boxes with the missing products of each reaction. For box B to C, ggust a mechanism for that reaction step. CO₂Et NaOEt EtOH A NaOEt EtOH Br H3O+ B

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.

Question

**Transcription for Educational Use: Reaction Mechanism Exercise**

**Problem Statement:**

Fill in the boxes with the missing products of each reaction. For box B to C, suggest a mechanism for that reaction step.

**Reaction Sequence:**

1. Starting Material: Ethyl 6-oxoheptanoate (EtO₂C(CH₂)₅CO₂Et)
- Reagent: Sodium ethoxide (NaOEt) in ethanol (EtOH).
- Result: Intermediate Product A.

2. Intermediate Product A
- Reagent: Sodium ethoxide (NaOEt) in ethanol (EtOH) with 1-bromohexane.
- Result: Intermediate Product B.

3. Intermediate Product B
- Conditions: Acidic hydrolysis (H₃O⁺) and heat (Δ).
- Result: Final Product C.

**Diagram Explanation:**

- The reaction starts with an ester compound, where a sodium ethoxide base will generate an enolate.
- In step 2, the enolate will react with 1-bromohexane through nucleophilic substitution to yield the alkylated product.
- The final step involves acidic hydrolysis and heating to convert the ester into an acid or another desired compound,
- Filling in products A, B, and C requires understanding the mechanisms of enolate chemistry and nucleophilic substitution. Suggest a detailed mechanism for creating Product B from A, then for converting B to C under acidic conditions.

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Step 1: Introduction to nucleophilic addition reaction

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Step 2: Reaction from A to C

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Step 4: Mechanism from B to C

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