FIGURE 13-22 Intagration of Hox and agmertation-protin inputa by a da-acting gulatory emant Lat: Ada-acting gatory damant of the Dgane govema the praon of Dpon in the abdomen by at of tranacption tactors ighe D praion ed odurta to the thora but not into the abdomen ina wid-tpe embryo. b- Mutatiora in thepective binding stus ahown dep oprion in vaiou patturra in the domen. Bnding a Sp. Soppy-panect Hot ard Hod, Lrabthor and Abdominal-A Ext. Extradertic En, Engalect H, Homothara. Data tom Gabalin a ME andR S Mann Dct intguion of ar and Segnaraton Ganainputs Duing Droophla Deveipmant"Natu 2004, 3- 13.4 Spatial Ragultion of Gane Epression in Devalopmant 493 Hox proteins and segmant-polarity proteins control appendage location CSACTING REGULATORY ELEMENT REPORTER-GENE EXPRESON AA A AS Wid ype Hox2 M TI 12 a Repredin AI-A ) Has mutation DerpredA- A A A S mutation M Depred I- 0 En muteton M In pAlA S En mutation Depre A-A m End, h mutetona M Depred in A-A

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Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.