FIGURE 10.1 Organization of sequences in bacterial chromo- somal DNA. Key features: • Most, but not all, bacterial species contain circular chromosomal DNA. CONCEPT CHECK: What types of sequences constitute most of a bacterial genome? Origin of replication • Most bacterial species contain a single type of chromosome, but it may be present in multiple copies. •A typical chromosome is a few million base pairs in length. • Several thousand different genes are interspersed throughout the chromosome. The short regions between adjacent genes are called intergenic regions. One origin of replication is required to initiate DNA replication. H Genes ant • Repetitive sequences may be interspersed throughout the chromosome. Intergenic regions w Repetitive sequences
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
What types of sequences constitute most of a bacterial genome

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