Homework Help is Here – Start Your Trial Now!
Science
Chemistry
explnation of the mechanism step by step

explnation of the mechanism step by step

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
See similar textbooks
icon
Related questions
Question

I need a break down and explnation of the mechanism step by step 

9 H® From water Sodium borohydride is An mild reducing Agent whivh converts Aldehydes and ketones to Alcohols. Step 2 Ps as . Jollous The mechanism requion atep1 Hyduide Trans Fer (attauk) ONat Na H- B-H H -> NO2 átepa: Abs hraution CH 20H H. ONa NO? 130
Transcribed Image Text:9 H® From water Sodium borohydride is An mild reducing Agent whivh converts Aldehydes and ketones to Alcohols. Step 2 Ps as . Jollous The mechanism requion atep1 Hyduide Trans Fer (attauk) ONat Na H- B-H H -> NO2 átepa: Abs hraution CH 20H H. ONa NO? 130
Reduction of 4-Nitrobenzaldehyde to 4-Nitrobenzyl Alcohol and Thin Layer Chromatography Background. Oxidation and reduction are among the most common organic reactions, both in the laboratory and in biochemical processes. There are literally dozens of different methods of oxidizing alcohols to ketones or aldehydes, and almost as many to reduce ketones or aldehydes back to alcohols. In this experiment, we will be using one of the most common reducing agents, sodium borohydride, to reduce 4-nitrobenzaldehyde to 4-nitrobenzyl alcohol. Note that sodium borohydride is not able to reduce the nitro group to the corresponding amine. The reaction occurs via a nucleophilic attack of the hydride on the carbonyl group. (See Karty, Chapter 17, page 821.) H. CH2OH NaBH4 (1) NO2 When running a chemical reaction, it is important to know when the reaction is complete. This information can prevent you from stopping a reaction too early or wasting time waiting for a reaction to finish. So how can you easily monitor the progress of the reaction, without using up most of the contents of the reaction mixture for NMR analyses? By far the most common technique used is Thin Layer Chromatography (TLC). Generally, TLC is a simple, effective and inexpensive method for separating and analyzing a mixture of compounds (such as the one that may be present half way through the reduction) using only a very small amount of the sample – less than a milligram. TLC is a qualitative technique. It does not give you information on how much of a given compound is in a sample. For details on how Thin Layer Chromatography works, see your lab text. You must read this section prior to performing this experiment.
Transcribed Image Text:Reduction of 4-Nitrobenzaldehyde to 4-Nitrobenzyl Alcohol and Thin Layer Chromatography Background. Oxidation and reduction are among the most common organic reactions, both in the laboratory and in biochemical processes. There are literally dozens of different methods of oxidizing alcohols to ketones or aldehydes, and almost as many to reduce ketones or aldehydes back to alcohols. In this experiment, we will be using one of the most common reducing agents, sodium borohydride, to reduce 4-nitrobenzaldehyde to 4-nitrobenzyl alcohol. Note that sodium borohydride is not able to reduce the nitro group to the corresponding amine. The reaction occurs via a nucleophilic attack of the hydride on the carbonyl group. (See Karty, Chapter 17, page 821.) H. CH2OH NaBH4 (1) NO2 When running a chemical reaction, it is important to know when the reaction is complete. This information can prevent you from stopping a reaction too early or wasting time waiting for a reaction to finish. So how can you easily monitor the progress of the reaction, without using up most of the contents of the reaction mixture for NMR analyses? By far the most common technique used is Thin Layer Chromatography (TLC). Generally, TLC is a simple, effective and inexpensive method for separating and analyzing a mixture of compounds (such as the one that may be present half way through the reduction) using only a very small amount of the sample – less than a milligram. TLC is a qualitative technique. It does not give you information on how much of a given compound is in a sample. For details on how Thin Layer Chromatography works, see your lab text. You must read this section prior to performing this experiment.
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Reaction Rates
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY
SEE MORE TEXTBOOKS