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Explain the Titrimetric profile of Lysine in figure 2

Explain the Titrimetric profile of Lysine in figure 2

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Explain the Titrimetric profile of Lysine in figure 2.
pka values that surround the zwitterion Zwitterion H. H3N*-Ć -COOH H3N* -C-CO" H2N–C- C0- H2N-C-CO- pka,=8.95 pka;=2.18 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 pH = 2.18 pH = 8.95 pH = 10.79 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 NH3+ NH3* NH3* NH2 pKa=10.79 Net charge: +2 +1 - 1 8.95+10.79 Isoelectric pH (pl) = = 9.87 Figure 2. Titrimetric profile of Lysine using theoretical pKa values
Transcribed Image Text:pka values that surround the zwitterion Zwitterion H. H3N*-Ć -COOH H3N* -C-CO" H2N–C- C0- H2N-C-CO- pka,=8.95 pka;=2.18 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 pH = 2.18 pH = 8.95 pH = 10.79 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 NH3+ NH3* NH3* NH2 pKa=10.79 Net charge: +2 +1 - 1 8.95+10.79 Isoelectric pH (pl) = = 9.87 Figure 2. Titrimetric profile of Lysine using theoretical pKa values
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