Explain the structure of basophils?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Explain the structure of basophils?

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Basophils are a type of WBCs (white blood cells). They are the least common type of the granulocytes. They represents about 0.5 to 1% of the circulating WBCs. Basophils are the largest type of the granulocyte. They functions in inflammatory reactions during the immune response and also in the formation of allergic diseases such as asthma, anaphylaxis, hay fever, and atopic dermatitis. They produce some compounds that coordinate the immune responses. They produce heparin that prevents the clotting of blood, serotonin and histamine that induce inflammation,

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Structure of basophils:

Basophil cells contain cytoplasmic granules that vague the nucleus under the microscope when it stained. When it is unstained, the nucleus is visible and has two or three lobes, but usually has two lobes. Their lobes are as well defined as of neutrophils. Their nucleus may appear as S-shaped. Basophils store histamine, which is a chemical compound secreted from the cells upon stimulation. When needed, these cells can be recruited out of the blood into tissue.

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