5. A 23-year-old man was admitted to a hospital for a planned surgical operation. When performing the surgical operation to remove a tumor from the upper section of the anterior pituitary, an isthmus of the posterior pituitary was 552 Chapter 9. Molecular endocrinology affected. In the postoperative period, in the patient polyuria developed. How to explain the patient symptom? For answer: a) name the hormones synthesized in the hypothalamus and secreted from the posterior lobe of the pituitary; b) draw a schematic mechanism of this hormone signal transduction;
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- 25. Patient a., 28 y/o, has been diagnosed with Ishchenko-Cushing’s disease. Which methods of treatment of Ishchenko-Cushing’s disease listed below can be referred to etiological? A. Unilateral adrenalectomyB. Bilateral adrenalectomyC. Gamma ray teletherapy of the pituitary gland areaD. All the above mentioned. Identify the endocrine organ described by each of the following statements. 1. located in the anterior neck; produces key hormones for metabolism 2. produces the hormones that are stored in the posterior pituitary 3. a mixed gland, located behind the stomach and close to the small intestine 4. paired glands suspended in the scrotum 5. bilobed gland located in the sella turcica 6. found in the pelvic cavity of the female, concerned with ova and female hormone production 7. found in the upper thorax overlying the heart; large during youth 8. found in the roof of the third ventricle of the brain 405II. A 45-ycar-old man complaincd of rapid weight loss, tachycardia, increased sweating, occasional clevated blood pressure and increased excitability. Additional screening revealed a tumor in the medulla of one of the adrenal glands. The paticnt was diagnosed with pheochromocytoma. a) draw a chart of the catecholamines synthesis in adrenal glands; b) name the hormone that has its synthesis increased in this discase, list its target organs, stimuli of synthesis and sceretion, target tissues and receptors; c) draw a chart of signal transduction of this hormone to adipocytes and the metabolic pathway of fat with increased rate in the Bpatient's adipocytes; c) list the physiological effects of this hormone and explain the causes of the discase symptoms.
- 1. The most common side effect or toxicity associated with the use of AEDs is related to CNS depression. These include ataxia and somnolence. Describe the two CNS effects. ATAXIA - SOMNOLENCE - II. Anticonvulsants are teratogenic. Name at least 2 teratogenic effects associated with anticonvulsants. Fill out the table below. Column 1 - Teratogenic Effect Column 2 - Drugs Implicated Column 3 - Manifestation eratogenic Effect Drugs Implicated ManifestA 50 year old male is experiencing fatigue, dizziness, and headaches with a rapid decline in his visual acuity. He treats his hypertension and type 2 diabetes with medications. His brow and jaw are enlarged (proganthism), his hands and feet and fingers are wide. His wedding ring no longer fits on his finger. He is obese and has a deep voice. What hormones are of greatest concern of this person? a.) GSH B.) ACTH C.) Prolactin d.) GH8 Which of the following statements) is/are descriptive of diabetes mellitus? I. It results from decrease in insulin production by the pancreas or the cell's insensitivity to insulin. TI. It may manifest as polyphagia and polydipsia. III. It leads to fatal complications like chronic renal failure and cardiovascular diseases. Select the correct response: Ionly Ill only Il only 1, ll, and Ill Il and Ill I and IlI I and II
- 48) Opioid receptor antagonist administration should be avoided in pregnancy unless absolutely needed, because death of the fetus could result from _______________. 48) Vasodilation Narcotic Withdrawal Malnutrition Acidity4. An 18-year-old girl lives in a mountain village, turned to an endocrinologist with complaints of general weakness, low body temperature, and mood deterioration. The patient was sent for a blood test for TTH and iodothyronine. The results of the analysis showed an increase in the concentration of TTH and a decrease in the concentration of T4. Explain: D. What diet should be followed in order to prevent this pathology; E. Describe the main stages of synthesis and draw a diagram of the regulation of thyroid hormone secretion. Why is it necessary to control the level of TSH in the blood when taking thyroxine?8) An endocrine case A woman seeks medical advice because she feels tired and listless. She also complains of gaining weight in the past year, although her appetite has decreased. Her friends have also commented that she seems low, or even depressed. When the doctor examines her, she measures a heart rate of 60 beats / minute, which is a little lower than normal, swollen face and dry, brittle hair. During the examination, she gets cold and freezes even if the temperature around is normally warm. The doctor suspects hypothyroidism, but before a final diagnosis she needs some information, including some blood tests. The results show high cholesterol levels, which is usually seen in hypothyroidism, extremely low thyroid hormone levels and high levels of TSH. These results showed that the woman suffered from a problem with the thyroid gland and not from the pituitary gland. Further tests showed that the woman had an autoimmune disease, Hashimoto's disease in which the thyroid follicle…
- A mother calls for an appointment for her 12-year-old son Daniel. He eats enormous amounts of food and seems to be thirsty all the time. His mother notes that Daniel seems to be going to the bathroom more frequently, and his soccer coach has relayed to her his concern that the boy is tired all the time. 1. What endocrine dysfunction is suggested by these signs and symptoms? 2. If Daniel does have the indicated dysfunction, what are the likely treatments? 3. What might be the prognosis for Daniel?1. The effect where one hormone allows/permits the target organ’s response to a second hormone (i.e. prolactin (PRL) and oxytocin) is known as a(n)__________ effect. 2. A patient presents with the following symptoms: Constipation, increased sensitivity to cold temperature, fatigue/run down/weakness, heavier and irregular menstrual periods, joint or muscle pain, paleness or dry skin, sadness or depression, thin, brittle hair or fingernails, weight gain, and a pronounced goiter. What is the probable diagnoisis? 3. True or False:- Most homeostatic control systems utilize some type of negative feedback system. 4. Oxytocin, Antidiuretic Hormone (ADH)/Vasopressin, epinephrine/adrenaline, norepinephrine/noradrenaline, growth hormone releasing hormone (GHRH) and other hormones made and secreted by neuronal cells are known as _____________ 5.True or False:- A trophic hormone is a hormone which is controlled by another hormone. 6. True or False:- A trophic hormone is a hormone which is…3. The wife of a 48-year-old diabetic client, who was discharged from the healthcare facility a week ago, calls the telehealth service. She sounds worried and says her husband has been showing strange symptoms, such as confusion, nervousness, and excessive hunger, for the past 2 days. He has also been complaining of blurred vision and dizziness. She tells the nurse that she had been administering insulin to her husband as directed by the healthcare provider but is not sure of the cause of his GV grivipost ard condition. ● insilo m What should the nurse tell the caller about the Jain Svizasox possible cause of these symptoms in the client? What possible measures should the nurse suggest the caller take to prevent further complications? 9, 10 Serie lamoo dilbs) bris sestdmun bris coulp emaslą onlsqsnq enoldbundani 1erW spor fnells