Explain the difference between the four primary blood types that are described by the ABO system. Be sure to address why these differences lead to the incompatibilities observed when it comes to blood donations and transfusions.

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**Explanation of Blood Types in the ABO System**

The ABO blood group system classifies blood into four main types: A, B, AB, and O. These types are determined by the presence or absence of specific antigens on the surface of red blood cells.

**Blood Type A**: Has A antigens on the surface of red blood cells and anti-B antibodies in the plasma. This means individuals with type A blood can receive type A or O blood, but not B or AB.

**Blood Type B**: Has B antigens on the surface and anti-A antibodies in the plasma. Individuals with type B blood can receive type B or O blood, but not A or AB.

**Blood Type AB**: Has both A and B antigens on the surface and no anti-A or anti-B antibodies in the plasma. This makes individuals with type AB blood universal recipients; they can receive A, B, AB, or O blood.

**Blood Type O**: Has no A or B antigens on the surface, but has anti-A and anti-B antibodies in the plasma. Individuals with type O blood are universal donors, but they can only receive type O blood.

**Incompatibilities in Blood Transfusions**

Incompatibility occurs when the recipient's immune system attacks the donor blood. This happens if the antigens in the donor blood do not match the antibodies in the recipient's plasma, which can lead to serious complications.

**Diagram Explanation**

The illustration, labeled "A," likely shows a diagram comparing the different blood types through visual representations of antigens and antibodies. Such diagrams usually highlight which blood types can donate to or receive from others, showing compatibility and incompatibility in transfusions.
Transcribed Image Text:**Explanation of Blood Types in the ABO System** The ABO blood group system classifies blood into four main types: A, B, AB, and O. These types are determined by the presence or absence of specific antigens on the surface of red blood cells. **Blood Type A**: Has A antigens on the surface of red blood cells and anti-B antibodies in the plasma. This means individuals with type A blood can receive type A or O blood, but not B or AB. **Blood Type B**: Has B antigens on the surface and anti-A antibodies in the plasma. Individuals with type B blood can receive type B or O blood, but not A or AB. **Blood Type AB**: Has both A and B antigens on the surface and no anti-A or anti-B antibodies in the plasma. This makes individuals with type AB blood universal recipients; they can receive A, B, AB, or O blood. **Blood Type O**: Has no A or B antigens on the surface, but has anti-A and anti-B antibodies in the plasma. Individuals with type O blood are universal donors, but they can only receive type O blood. **Incompatibilities in Blood Transfusions** Incompatibility occurs when the recipient's immune system attacks the donor blood. This happens if the antigens in the donor blood do not match the antibodies in the recipient's plasma, which can lead to serious complications. **Diagram Explanation** The illustration, labeled "A," likely shows a diagram comparing the different blood types through visual representations of antigens and antibodies. Such diagrams usually highlight which blood types can donate to or receive from others, showing compatibility and incompatibility in transfusions.
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INTRODUCTION

ABO blood grouping

The ABO blood grouping was discovered by Karl Landsteiner.

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