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Biomedical Instrumentation Systems

Biomedical Instrumentation Systems

1st Edition

ISBN:9781133478294

Author:Chatterjee

Publisher:Chatterjee

Chapter24: New Technologies And Advances In Medical Instrumentation

Section: Chapter Questions

Problem 3P

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Explain a ideal molecular polymer design for sustainable syringes in medicine

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Describe two different applications of superparamagnetic particles in bio-medicines and what are the advantages of using superparamagnetic particles.
Give introduction to Chain-Growth Polymers :
a) List three biomaterials that are used in cancer diagnosis and therapeutic.b) List three biomaterials that are used in scaffold applications.
Polymeric materials have a widely used in vascular grafts, artificial heart valves, sutural materials, dentures, joints, prostheses lenses, prostheses eye, prostheses ear, cosmetic and reconstructive surgery. Why?
Compare the toxicity, tunability, yield and bioactivity aspects of synthetic biomaterials vs. natural biomaterials for tissueenginnering applications
Nanoparticles were added in a liquid to prompt the medication release, and it was observed that 5 mg of the medication was released in 1 liter of PBS, which accounted for 60% of the total amount of the drug. While producing an equivalent number of nanoparticles, 5 ml of 10 mg ml−1 of the drug was added. What is the efficiency of encapsulation?
)Give an example of Class III Biomedical device? Discuss why it is classified as Class III?
Describe how structural information can be used to assist in drug development.
Polymer nanoparticles, Microparticles and hydrogels have been developed for slow and sustained drug release for slow and sustained drug release application; mark all that apply below: 1)Drug release from hydrogels can be via (a) drug diffusion, (b) degradation of the polymeric matrix and (c) swelling 2) PLGA degrades to lactic acid and glycolic acid, which are not biocompatible 3) Drug release can be triggered through internal and external stimuli - I.e. by use of pH labile chemistries or external triggers 4) Burst release describes the initial faster release rates often observed in drug delivery system, which is then followed by sustained release 5) while burst release is observed with polymer nanoparticles, it is not observed from hydrogels
7) Which one of the below given properties belongs to ceramic based biomaterials ? a) Easier to shape at any temperature b) May contain organic material portions c) Do not react with the biological enviroment d) Low compressive strength 8) Sort the below given properties for Natural and Synthetic Polymers Can tailor physical, chemical, mechanical and degradative properties Low mechanical properties Non-assurance of pathogen removal Easily mass produced and sterilized
Give information about the microchip that could control drugs invented by Robert Langer and Michael Cima. When the studies started, how did the idea come out, who found it, which university the studies were carried out, what exactly does the product work, when was the patent obtained? Write important information about this polymer wafer (Please don't give short answer)
Which of the following statements about electron microscopy are true? a) Most existing protein structures have been resolved using electron microscopy b) Electron microscopy is not used in structural biology as it can not give as high a resolution as X-ray crystallography and NMR c) The smaller a protein, the easier it is to solve its structure with electron microscopy d) By taking pictures of the same protein frozen in ice thousands of times and then adding them together, you get a high-resolution image of the protein e) The first protein structure with true atomic resolution was solved using electron microscopy last year

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