Experiment I: Scientists took two types of human epithelial cells and placed them in an experimental system that could measure intracellular (IN) and extracellular concentration (OUT) of 3 substances: Na+, ATP and Glucose. Cell type A was nonmutant whereas cell type B had a mutation in a transmembrane protein. At the beginning, middle and end of the experiment, concentrations were measured for all three substances as shown below. Cell type A (non-mutant) Time IN [Na+] 0 10 ms 20 ms Concentration in mM 200 150 150mM 25mM 150mM 100 Q1. Analyze the intracellular concentration changes in the table (above) and the graph (below left). Label the key at the bottom left. Graph the extracellular concentration changes in this data set using the graph below right and the same key. With cell image on bottom right, diagram what is happening using arrows and labels for the transported substance. And finally, at the bottom of the page describe what is happening using words i.e. powers the movement of in/out of the cell. Intracellular concentrations Extracellular concentrations 50- 0 OUT [Na+] 15mM KEY 140mM 15mM 10 IN [ATP] 200mM 70mM 70mM Time in milliseconds 20 Concentration in mM 200 150 100 IN [Glu] 5mM 5mM 135mM 50 OUT [Glu] 200mM 200mM 55mM 0 I 10 Time in milliseconds 20
Experiment I: Scientists took two types of human epithelial cells and placed them in an experimental system that could measure intracellular (IN) and extracellular concentration (OUT) of 3 substances: Na+, ATP and Glucose. Cell type A was nonmutant whereas cell type B had a mutation in a transmembrane protein. At the beginning, middle and end of the experiment, concentrations were measured for all three substances as shown below. Cell type A (non-mutant) Time IN [Na+] 0 10 ms 20 ms Concentration in mM 200 150 150mM 25mM 150mM 100 Q1. Analyze the intracellular concentration changes in the table (above) and the graph (below left). Label the key at the bottom left. Graph the extracellular concentration changes in this data set using the graph below right and the same key. With cell image on bottom right, diagram what is happening using arrows and labels for the transported substance. And finally, at the bottom of the page describe what is happening using words i.e. powers the movement of in/out of the cell. Intracellular concentrations Extracellular concentrations 50- 0 OUT [Na+] 15mM KEY 140mM 15mM 10 IN [ATP] 200mM 70mM 70mM Time in milliseconds 20 Concentration in mM 200 150 100 IN [Glu] 5mM 5mM 135mM 50 OUT [Glu] 200mM 200mM 55mM 0 I 10 Time in milliseconds 20
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
Related questions
Question
need help with answering Q1 and understanding on how to do it.
Thanks!
![**Experiment I:**
Scientists took two types of human epithelial cells and placed them in an experimental system that could measure intracellular (IN) and extracellular concentration (OUT) of three substances: Na⁺, ATP, and Glucose. Cell type A was non-mutant whereas cell type B had a mutation in a transmembrane protein. At the beginning, middle, and end of the experiment, concentrations were measured for all three substances as shown below.
**Cell type A (non-mutant):**
| Time | IN [Na⁺] | OUT [Na⁺] | IN [ATP] | IN [Glu] | OUT [Glu] |
|-------|----------|-----------|----------|----------|-----------|
| 0 ms | 150mM | 15mM | 200mM | 5mM | 200mM |
| 10 ms | 25mM | 140mM | 70mM | 5mM | 200mM |
| 20 ms | 150mM | 15mM | 70mM | 135mM | 55mM |
**Q1.** Analyze the intracellular concentration changes in the table above and the graph below left. Label the key at the bottom left. Graph the extracellular concentration changes in this data set using the graph below right and the same key. With the cell image on the bottom right, diagram what is happening using arrows and labels for the transported substance. And finally, at the bottom of the page describe what is happening using words i.e., ___ powers the movement of ___ in/out of the cell.
**Graphs Explained:**
1. **Intracellular Concentrations (Left Graph):**
- The graph plots concentrations (in mM) against time (in milliseconds).
- The circle represents sodium (Na⁺) concentration, which initially decreases at 10 ms and returns to the initial level by 20 ms.
- The square represents ATP concentration, which decreases and remains constant between 10 ms and 20 ms.
- The triangle represents glucose concentration, which rises significantly by 20 ms.
2. **Extracellular Concentrations (Right Graph):**
- Although not completed in the image, this graph should plot the changes in extracellular Na⁺, ATP, and Glucose concentrations over time](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff1541ca2-1ddc-42c8-8744-b2cad194e12f%2F38c7b973-52e9-4e9d-af52-1d4d5d898090%2F8rnrgp_processed.png&w=3840&q=75)
Transcribed Image Text:**Experiment I:**
Scientists took two types of human epithelial cells and placed them in an experimental system that could measure intracellular (IN) and extracellular concentration (OUT) of three substances: Na⁺, ATP, and Glucose. Cell type A was non-mutant whereas cell type B had a mutation in a transmembrane protein. At the beginning, middle, and end of the experiment, concentrations were measured for all three substances as shown below.
**Cell type A (non-mutant):**
| Time | IN [Na⁺] | OUT [Na⁺] | IN [ATP] | IN [Glu] | OUT [Glu] |
|-------|----------|-----------|----------|----------|-----------|
| 0 ms | 150mM | 15mM | 200mM | 5mM | 200mM |
| 10 ms | 25mM | 140mM | 70mM | 5mM | 200mM |
| 20 ms | 150mM | 15mM | 70mM | 135mM | 55mM |
**Q1.** Analyze the intracellular concentration changes in the table above and the graph below left. Label the key at the bottom left. Graph the extracellular concentration changes in this data set using the graph below right and the same key. With the cell image on the bottom right, diagram what is happening using arrows and labels for the transported substance. And finally, at the bottom of the page describe what is happening using words i.e., ___ powers the movement of ___ in/out of the cell.
**Graphs Explained:**
1. **Intracellular Concentrations (Left Graph):**
- The graph plots concentrations (in mM) against time (in milliseconds).
- The circle represents sodium (Na⁺) concentration, which initially decreases at 10 ms and returns to the initial level by 20 ms.
- The square represents ATP concentration, which decreases and remains constant between 10 ms and 20 ms.
- The triangle represents glucose concentration, which rises significantly by 20 ms.
2. **Extracellular Concentrations (Right Graph):**
- Although not completed in the image, this graph should plot the changes in extracellular Na⁺, ATP, and Glucose concentrations over time
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 1 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education