Exercise 0.3 Suppose that vaccination strategies are implemented for newborns, so that not all newborns are considered susceptible. If the vaccination rate per capita is p, then a newborn becomes vaccinated with probability p. The modified model now takes the form ds = (1-p)µN - BS- dt - μS - PS N dI = BS- N (μ + y) I (0.3) dt dV = pμN +I+pS - µV dt (a) Find the basic reproduction number Ro by the next generation matrix method. (b) Analyze the stability of the disease-free equilibrium of this model

Linear Algebra: A Modern Introduction
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Chapter7: Distance And Approximation
Section7.3: Least Squares Approximation
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Exercise 0.3 Suppose that vaccination strategies are implemented for newborns, so that not
all newborns are considered susceptible. If the vaccination rate per capita is p, then a newborn
becomes vaccinated with probability p. The modified model now takes the form
ds
=
(1-p)µN - BS-
dt
S - μS - PS
N
=
BS-
N
(μ + y) I
(0.3)
dt
dV
=
pμN+I+pS - µV
dt
(a) Find the basic reproduction number Ro by the next generation matrix method.
(b) Analyze the stability of the disease-free equilibrium of this model
Exercise 0.4 Consider the following discrete time epidemic model
Sn+1
=
(1-p)v + Sn - B-
BSn In
- µSn
N
In+1
(0.4)
=
In + 3√n In
- In - μIn
N
Rn+1
=
vp + Rn+In - μRn
i. Identify the model and describe the parameters involved in the model.
ii. Determine the basic reproduction number Ro using the next generation matrix method.
dI
[
Transcribed Image Text:Exercise 0.3 Suppose that vaccination strategies are implemented for newborns, so that not all newborns are considered susceptible. If the vaccination rate per capita is p, then a newborn becomes vaccinated with probability p. The modified model now takes the form ds = (1-p)µN - BS- dt S - μS - PS N = BS- N (μ + y) I (0.3) dt dV = pμN+I+pS - µV dt (a) Find the basic reproduction number Ro by the next generation matrix method. (b) Analyze the stability of the disease-free equilibrium of this model Exercise 0.4 Consider the following discrete time epidemic model Sn+1 = (1-p)v + Sn - B- BSn In - µSn N In+1 (0.4) = In + 3√n In - In - μIn N Rn+1 = vp + Rn+In - μRn i. Identify the model and describe the parameters involved in the model. ii. Determine the basic reproduction number Ro using the next generation matrix method. dI [
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