EXAMPLE Ah nas a rare X-linked dominant condition called amelogenesis Imperfecta, whicn results in weak brown tooth enamel. He marries a woman with normal teeth. They produce a daughter with normal teeth. This daughter's normal teeth resulted from one nondisjunction event during the formation of either the egg or sperm. a. In which parent did the nondisjunction occur? Explain. b. Did nondisjunction occur at meiosis I or lI? 3 c. What sex chromosomes are in the daughter's somatic cells? Show the allele/s for tooth enamel (normal or amelogenesis imperfecta) on the appropriate sex chromosome/s.

Human Anatomy & Physiology (11th Edition)
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5. Sometimes nondisjunction will occur in a parent that
has normal chromosome numbers and result in an
offspring that has abnormal number of chromosomes.
The phenotype of the affected offspring will often allow
geneticists to determine in which parent and during
which division of meiosis the nondisjunction occurred. In
each of the examples below, assume the parents have a normal diploid chromosome
complement.
EXAMPLE 1: A man has a rare X-linked dominant condition called amelogenesis imperfecta, which
results in weak brown tooth enamel. He marries
woman with normal teeth. They produce a
daughter with normal teeth. This daughter's normal teeth resulted from one nondisjunction
event during the formation of either the egg or sperm.
a. In which parent did the nondisjunction occur?
Explain.
b. Did nondisjunction occur at meiosis I or I1?
3
c. What sex chromosomes are in the daughter's somatic cells? Show the allele/s for
tooth enamel (normal or amelogenesis imperfecta) on the appropriate sex
chromosome/s.
3
Transcribed Image Text:5. Sometimes nondisjunction will occur in a parent that has normal chromosome numbers and result in an offspring that has abnormal number of chromosomes. The phenotype of the affected offspring will often allow geneticists to determine in which parent and during which division of meiosis the nondisjunction occurred. In each of the examples below, assume the parents have a normal diploid chromosome complement. EXAMPLE 1: A man has a rare X-linked dominant condition called amelogenesis imperfecta, which results in weak brown tooth enamel. He marries woman with normal teeth. They produce a daughter with normal teeth. This daughter's normal teeth resulted from one nondisjunction event during the formation of either the egg or sperm. a. In which parent did the nondisjunction occur? Explain. b. Did nondisjunction occur at meiosis I or I1? 3 c. What sex chromosomes are in the daughter's somatic cells? Show the allele/s for tooth enamel (normal or amelogenesis imperfecta) on the appropriate sex chromosome/s. 3
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