Eukaryotic gene expression. The following pre-MRNA undergoes splicing and contains a single open reading frame (ORF). exon 1 intron exon 2 wild-type pre-MRNA 5'.UAUGUUUUAGUAUAUAGCUAGU.-3' What is the sequence of the tripeptide after splicing and translation have occurred? (Write single CAPITAL letters for amino acids, with no spaces between.) A series of mutant pre-MRNAS were sequenced. Find the site of each mutation by referring to the wild-type pre-mRNA (above). Then identify the type of mutation in the polypeptide after splicing and translation have occurred. (In the spaces provided, write: "silent", "missense", "nonsense", or "frameshift") 5'.UAUGUUUUCGUAUAUAGCUAGU..-3' 5'.UAUGUUUUAGUAUAUAGGUAGU.-3' 5'.UAUGUUUUAGUAAAUAGCUAGU.-3'

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Eukaryotic gene expression. The following pre-MRNA undergoes splicing and contains a single open reading frame (ORF).
exon 1
intron
exon 2
wild-type pre-MRNA
5'.UAUGUUUUAGUAUAUAGCUAGU.-3'
What is the sequence of the tripeptide after splicing and translation have occurred? (Write single CAPITAL letters for amino acids, with
no spaces between.)
A series of mutant pre-MRNAS were sequenced. Find the site of each mutation by referring to the wild-type pre-mRNA (above). Then
identify the type of mutation in the polypeptide after splicing and translation have occurred. (In the spaces provided, write: "silent",
"missense", "nonsense", or "frameshift".)
5'.UAUGUUUUCGUAUAUAGCUAGU.-3
5'.UAUGUUUUAGUAUAUAGGUAGU.-3'
5'.UAUGUUUUAGUAAAUAGCUAGU.-3'
Transcribed Image Text:Eukaryotic gene expression. The following pre-MRNA undergoes splicing and contains a single open reading frame (ORF). exon 1 intron exon 2 wild-type pre-MRNA 5'.UAUGUUUUAGUAUAUAGCUAGU.-3' What is the sequence of the tripeptide after splicing and translation have occurred? (Write single CAPITAL letters for amino acids, with no spaces between.) A series of mutant pre-MRNAS were sequenced. Find the site of each mutation by referring to the wild-type pre-mRNA (above). Then identify the type of mutation in the polypeptide after splicing and translation have occurred. (In the spaces provided, write: "silent", "missense", "nonsense", or "frameshift".) 5'.UAUGUUUUCGUAUAUAGCUAGU.-3 5'.UAUGUUUUAGUAUAUAGGUAGU.-3' 5'.UAUGUUUUAGUAAAUAGCUAGU.-3'
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