Ethynylcyclopentane, first reacts with sodium amide. The product formed in the first step reacts with bromocyclohexane in the second step. What is the final major product of these reactions? 1) NaNH2 2) CH,Br II IV
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![Ethynylcyclopentane, first reacts with sodium amide. The product formed in the first step reacts
with bromocyclohexane in the second step. What is the final major product of these reactions?
1) NaNH2
2) CgH1,Br
II
IV
II](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F5bd4d0cb-2c8a-45da-9e56-d8cbfe321372%2F5d3df430-e0d3-48fc-84c9-5047c0fefc7b%2Fc5nzvak_processed.jpeg&w=3840&q=75)
![Which statements apply to an SN2 reaction?
I) The rate limiting step of the reaction involves the alkyl halide and the nucleophile
1I) The order of reactivity is methyl > 1°>2°>3°.
111) The rate limiting step of the reaction involves only the alkyl halide
IV) There is an carbocation intermediate.
OII, IV
OII, II
I, IV
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