Draw the missing organic structures or select the missing reagents in the following multistep synthesis. Ignore any inorganic byproducts formed. Incorrect, 1 attempt remaining
Draw the missing organic structures or select the missing reagents in the following multistep synthesis. Ignore any inorganic byproducts formed. Incorrect, 1 attempt remaining
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Draw the missing organic structures or select the missing reagents in the
following multistep synthesis. Ignore any inorganic byproducts formed.
Incorrect, 1 attempt remaining
ثلا
Select to Draw
Q
X
1. NaOCH₂CH3
2. C6HsCH₂Br (1 equiv)
H3O+
heat
(
O
Select to Draw
1. NaOCH₂CH3
2. CH3Br (1
equiv)
Select to Draw
Expert Solution

Step 1: Malonate ester synthesis
Diethyl malonate ester contains an active methylene group, (CH2 group attached with two carbonyl groups). In the presence of a base, the diethyl malonate ester forms a malonate anion, which acts as a nucleophile and gives a nucleophilic substitution reaction with the alkyl bromide.
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