#55 help ### Claisen Condensation Reaction**Objective:** Draw the major product of the Claisen condensation reaction between two molecules of this ester. Ignore inorganic byproducts.**Starting Material:** The structure of the ester is provided, featuring a carbonyl group (C=O) with an ethyl group (–CH₂CH₃) and a methoxy group (–OCH₃) attached on either side of the carbonyl carbon.**Reaction Conditions:**1. **Reagents:** - Sodium methoxide (NaOCH₃) in methanol (CH₃OH) - Followed by an acidic workup**Diagram Explanation:**- A skeletal formula of an ester is shown with the following components: - A two-carbon chain attached to the carbonyl group. - The carbonyl carbon is bonded to an oxygen which is further bonded to a methyl group (methoxy group).- The arrow indicates that this ester undergoes a reaction under the given conditions.- The reaction conditions are outlined next to the arrow, specifying the use of a base (NaOCH₃ in CH₃OH) and an acidic workup.**Expected Outcome:**The Claisen condensation involves the base-catalyzed formation of a β-keto ester by the condensation of two ester molecules. After the removal of an α-hydrogen and subsequent nucleophilic acyl substitution, the deprotonation and acid workup will yield the final product. The ester in question will react with itself, leading to the formation of a new carbon-carbon bond. The structure of the product is not shown, and users are encouraged to visualize or draw the expected β-keto ester product formed as a result of this reaction.

Claisen condensation: Esters undergo self condensation in presence of a base followed by work-up to form the product.The answer is:

Answered: Draw the major product of the Claisen…

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Draw the major product of the Claisen condensation reaction between two molecules of this ester. Ignore inorganic byproducts. O 1. NaOCH 3/ CH3OH 2. Acidic workup

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

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Concept explainers

Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.

Question

#55 help

### Claisen Condensation Reaction

**Objective:**
Draw the major product of the Claisen condensation reaction between two molecules of this ester. Ignore inorganic byproducts.

**Starting Material:**
The structure of the ester is provided, featuring a carbonyl group (C=O) with an ethyl group (–CH₂CH₃) and a methoxy group (–OCH₃) attached on either side of the carbonyl carbon.

**Reaction Conditions:**

1. **Reagents:**
- Sodium methoxide (NaOCH₃) in methanol (CH₃OH)
- Followed by an acidic workup

**Diagram Explanation:**

- A skeletal formula of an ester is shown with the following components:
- A two-carbon chain attached to the carbonyl group.
- The carbonyl carbon is bonded to an oxygen which is further bonded to a methyl group (methoxy group).

- The arrow indicates that this ester undergoes a reaction under the given conditions.

- The reaction conditions are outlined next to the arrow, specifying the use of a base (NaOCH₃ in CH₃OH) and an acidic workup.

**Expected Outcome:**

The Claisen condensation involves the base-catalyzed formation of a β-keto ester by the condensation of two ester molecules. After the removal of an α-hydrogen and subsequent nucleophilic acyl substitution, the deprotonation and acid workup will yield the final product. The ester in question will react with itself, leading to the formation of a new carbon-carbon bond.

The structure of the product is not shown, and users are encouraged to visualize or draw the expected β-keto ester product formed as a result of this reaction.

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