dominant allele. If the genotype could be either AA or Aa, write A-. (Do not assume that those marrying into the family have no family history.) Then calculate the percent penetrance of allele A. a. Pedigree H-Autosomal recessive Aa ya A Aa 9.9 199 Aa 10 199 99 aa 10 Aa sa A 9.9 AQ ac BEDO H Autosomal dominant with incomplete penetrance.
dominant allele. If the genotype could be either AA or Aa, write A-. (Do not assume that those marrying into the family have no family history.) Then calculate the percent penetrance of allele A. a. Pedigree H-Autosomal recessive Aa ya A Aa 9.9 199 Aa 10 199 99 aa 10 Aa sa A 9.9 AQ ac BEDO H Autosomal dominant with incomplete penetrance.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:PART FIVE-INCOMPLETE PENETRANCE
4. Write in the most likely genotype of everyone in the pedigree assuming: (a) autosomal
recessive inheritance, and (b) autosomal dominant inheritance with incomplete pene-
trance of the dominant allele. If the genotype could be either AA or Aa, write A-. (Do
not assume that those marrying into the family have no family history.) Then calculate
the percent penetrance of allele A.
a. Pedigree H-Autosomal recessive
Aa
Aa
Aa
Aa
aa
99
199
Aa
Aa
40
99
aa
99
Aa
aq
ja
aq AQ
aq
b. Pedigree H-Autosomal dominant with incomplete penetrance
AQ
A
Aa
Aa
Aa
Aa
Aa
c. Estimate of the percent penetrance of allele A:
x 100
=>
# affected
#genotype
heterozygous
Aa
aa
log
A
aa
A
Jaa
aq
6
aq
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