Devise the most efficient synthesis for the carboxylic acid below using a starting material and reagents from the tables. Give your route by specifying he number of the starting material followed by the letters of the reagents you would use beginning with the first step. The answer 4th means treat /-butanol (4) with conc. HCl(f) then treat the product with KOH in alcohol(h). Starting materials Reagents Br a Mg/dry ether OH c NaCN/THF or DMF *25 b 1. CO₂ 2. acidic workup d NaCN/dil. aqueous H₂SO4 3 OH e Aqueous H₂SO4 at reflux g PBr3 f Conc. HCI or HCI (gas) h KOH/alcohol Hot 4 i KMnO4/H₂O* j Na₂ CrO₂ / aqueous H₂SO4 k 1. BH₂/THF 2. H₂O₂laq. NaOH I 요
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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Subject :- Chemistry
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