Determine the product(s) formed when cyclohexene is treated with the following reagents. Br HO. HO Br NBS DMSO, H20 Br 'Br , CH;CH>OH H2SO4 [1] BH3 [2] H2O2, HO Br [1] 9-BBN [2] H202, HO OCH,CH, OH Br OCH,

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Chapter1: Chemical Foundations
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**Title: Reaction Products of Cyclohexene with Various Reagents**

**Introduction:**
This instructional material explores the products formed when cyclohexene undergoes different chemical reactions with specified reagents. Cyclohexene, a cyclic alkene, can react in various ways depending on the conditions and reagents used.

**Reagents and Reaction Pathways:**

1. **Reagent: NBS, DMSO, H2O**
   - **Direction:** North
   - **Expected Product:** Bromohydrin formation where NBS (N-bromosuccinimide) in DMSO/H2O results in the formation of a bromohydrin on cyclohexene.
   
2. **Reagent: [1] BH3, [2] H2O2, HO⁻**
   - **Direction:** East
   - **Expected Product:** Hydroboration-oxidation results in the anti-Markovnikov addition of water, producing an alcohol.
   
3. **Reagent: [1] 9-BBN, [2] H2O2, HO⁻**
   - **Direction:** South
   - **Expected Product:** Similar to the BH3 reaction, the hydroboration-oxidation with 9-BBN (9-borabicyclo[3.3.1]nonane) also gives an anti-Markovnikov alcohol.
   
4. **Reagent: CH3CH2OH, H2SO4**
   - **Direction:** West
   - **Expected Product:** This reaction involves alcohol addition, potentially resulting in ether formation from cyclohexene due to sulfuric acid catalysis.

**Product Illustrations:**
To the left of the main diagram are possible products depicted in structural form. They include variations like bromohydrins, different stereochemical configurations of alcohols, and ethers.

**Interpretation of Products:**
- The placement of OH and Br groups implies regioselectivity and stereochemistry important in determining the major and minor products of each reaction.
- Each illustrated compound on the left correlates with specific reagents showing transformed cyclohexene into expected products based on mechanistic pathways.

**Conclusion:**
This diagram effectively outlines the transformations of cyclohexene when reacted with specific reagents, illustrating potential products including bromohydrins, alcohols, and ethers. Understanding these reactions is crucial for mastery of organic synthesis concepts, specifically within
Transcribed Image Text:**Title: Reaction Products of Cyclohexene with Various Reagents** **Introduction:** This instructional material explores the products formed when cyclohexene undergoes different chemical reactions with specified reagents. Cyclohexene, a cyclic alkene, can react in various ways depending on the conditions and reagents used. **Reagents and Reaction Pathways:** 1. **Reagent: NBS, DMSO, H2O** - **Direction:** North - **Expected Product:** Bromohydrin formation where NBS (N-bromosuccinimide) in DMSO/H2O results in the formation of a bromohydrin on cyclohexene. 2. **Reagent: [1] BH3, [2] H2O2, HO⁻** - **Direction:** East - **Expected Product:** Hydroboration-oxidation results in the anti-Markovnikov addition of water, producing an alcohol. 3. **Reagent: [1] 9-BBN, [2] H2O2, HO⁻** - **Direction:** South - **Expected Product:** Similar to the BH3 reaction, the hydroboration-oxidation with 9-BBN (9-borabicyclo[3.3.1]nonane) also gives an anti-Markovnikov alcohol. 4. **Reagent: CH3CH2OH, H2SO4** - **Direction:** West - **Expected Product:** This reaction involves alcohol addition, potentially resulting in ether formation from cyclohexene due to sulfuric acid catalysis. **Product Illustrations:** To the left of the main diagram are possible products depicted in structural form. They include variations like bromohydrins, different stereochemical configurations of alcohols, and ethers. **Interpretation of Products:** - The placement of OH and Br groups implies regioselectivity and stereochemistry important in determining the major and minor products of each reaction. - Each illustrated compound on the left correlates with specific reagents showing transformed cyclohexene into expected products based on mechanistic pathways. **Conclusion:** This diagram effectively outlines the transformations of cyclohexene when reacted with specific reagents, illustrating potential products including bromohydrins, alcohols, and ethers. Understanding these reactions is crucial for mastery of organic synthesis concepts, specifically within
**Title: Products of But-1-ene with Various Reagents**

**Introduction:**

This guide explores the chemical reactions and products formed when but-1-ene is treated with various reagents. Understanding these reactions is crucial in organic chemistry, as it helps predict the outcomes of alkenes reacting with different substances.

**Diagram Explanation:**

The central structure in the diagram is but-1-ene, a four-carbon alkene with a double bond between the first and second carbon atoms.

**Reagent Reactions:**

1. **With HBr:**
   - The reaction of but-1-ene with HBr leads to the addition of hydrogen (H) and bromine (Br) across the double bond, resulting in the formation of 2-bromobutane.

2. **With Br2:**
   - When but-1-ene is treated with Br2, the double bond is broken, and a bromine atom adds to each of the previously double-bonded carbons, forming 1,2-dibromobutane.

3. **With Br2/CH3OH:**
   - In the presence of bromine and methanol (CH3OH), a reaction known as bromohydrin formation occurs, leading to the methoxy-bromo product 2-methoxy-3-bromobutane.

4. **With Br2/H2O:**
   - This reaction produces a bromohydrin, where water participates, resulting in 2-bromo-3-hydroxybutane.

**Product Structures:**

The diagram includes nine possible structures for the reaction products, showing the orientation and bonding of bromine, hydroxyl (OH), and methoxy (OCH3) groups with the butane backbone.

**Conclusion:**

The reactions of but-1-ene with these reagents demonstrate fundamental concepts in organic chemistry, particularly electrophilic addition reactions and the formation of halohydrins and bromohydrins. Understanding these reactions facilitates the prediction of product structures in synthetic organic chemistry.
Transcribed Image Text:**Title: Products of But-1-ene with Various Reagents** **Introduction:** This guide explores the chemical reactions and products formed when but-1-ene is treated with various reagents. Understanding these reactions is crucial in organic chemistry, as it helps predict the outcomes of alkenes reacting with different substances. **Diagram Explanation:** The central structure in the diagram is but-1-ene, a four-carbon alkene with a double bond between the first and second carbon atoms. **Reagent Reactions:** 1. **With HBr:** - The reaction of but-1-ene with HBr leads to the addition of hydrogen (H) and bromine (Br) across the double bond, resulting in the formation of 2-bromobutane. 2. **With Br2:** - When but-1-ene is treated with Br2, the double bond is broken, and a bromine atom adds to each of the previously double-bonded carbons, forming 1,2-dibromobutane. 3. **With Br2/CH3OH:** - In the presence of bromine and methanol (CH3OH), a reaction known as bromohydrin formation occurs, leading to the methoxy-bromo product 2-methoxy-3-bromobutane. 4. **With Br2/H2O:** - This reaction produces a bromohydrin, where water participates, resulting in 2-bromo-3-hydroxybutane. **Product Structures:** The diagram includes nine possible structures for the reaction products, showing the orientation and bonding of bromine, hydroxyl (OH), and methoxy (OCH3) groups with the butane backbone. **Conclusion:** The reactions of but-1-ene with these reagents demonstrate fundamental concepts in organic chemistry, particularly electrophilic addition reactions and the formation of halohydrins and bromohydrins. Understanding these reactions facilitates the prediction of product structures in synthetic organic chemistry.
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