Deterioration must be strictly avoided when drying pharmaceutical products. Furthermore, such products are often produced from a nonaqueous solvent such as ethanol, methanol, acetone, etc. Explain why a closed-cycle spray dryer using nitrogen is frequently a good choice of dryer

Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
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Deterioration must be strictly avoided when drying pharmaceutical products. Furthermore, such products are often produced from a nonaqueous solvent such as ethanol, methanol, acetone, etc. Explain why a closed-cycle spray dryer using nitrogen is frequently a good choice of dryer

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Step 1

The reason for the usage of closed-cycle spray dryer with nitrogen for drying the pharmaceutical products is to be mentioned.

Step 2

Closed-cycle spray dryers is a type of dryer where the solution are sprayed in an environment of nitrogen and the products are dried where base is solvent.

Both the products as well as the solvent are recovered completely here.

These types of dryers are useful in:-

1. Handling of the respective solvents

2. Products where sensitivity of heat is there

3. Inhibition of oxidation of the products that must be dried

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