Q: Misconception: Evolution results in progress; organisms are always getting better through evolution.…
A: Correct statement regarding the evolution. Given statement:- Misconception: Evolution results in…
Q: what is the relationship between healthy child development and income and social status in Canada
A: The population will have an influence on the resources of the given region at carrying capacity, but…
Q: Q) Plants that grow in saline water are called
A:
Q: 1. Give the Recombination Frequency of the following and show your solutions. a) Parents: AAbb x…
A:
Q: Given the following DNA sequences for cytochrome c, answer the question below. In one paragraph,…
A: Very closely related species have more amino acid sequence similarities in the same protein. The…
Q: 16. Ouabain is a naturally occuring substance that inhibits the Na-K-ATPase with high affinity. When…
A: Ouabain is a cardiac glycoside which is involved with inhibiting the Na+/ K+ ATPase pump. It is not…
Q: 5. Structure that develops into the seeds Stigma Style Ovary 1- 2- 3-
A:
Q: What are the correct codons of the MRNA from the given DNA strand th needs to be transcribed? *…
A: Sense strand It is also called as the coding strand , plus strand or the non template strand. The…
Q: List the evidences of evolution that philippine tarsier is an endemic species.
A: Philippine Tarsiers are basically haplorrhine primates which belongs to the family Tarsiidae.…
Q: Basha: A blood type, blue eye color, normal skin condition, carrier of cystic fibrosis gene, and…
A: In one sense, the term “genotype”—like the term “genome”—refers to the entire set of genes in the…
Q: Describe Mendels hypothesis of particulate inheritance
A: Before Mendel, scientists agreed that the traits of two parents blend or mix together to create an…
Q: Which of the following situations is a density - dependent limiting factor? Choose only one. -…
A: Introduction Density-dependent limiting factors tend to be biotic—having to do with living…
Q: motor protein(s) that can carry vesicles along microtubules?
A: Motor proteins -The last element required for the vesicle transport system is the motor protein.…
Q: 216 Inquiry into Life Laboratory Manual, 16th Edition ©2020 Mader Experimental Procedure: Wing…
A:
Q: What are the different modifications of adventitious roots? Explain with examples.
A: Adventitious Roots: Adventitious roots are nonroot plant roots that arise during normal development…
Q: Elaborate on the significance of DNA packaging in the inheritance and transmission of traits.
A: The DNA or deoxyribonucleic acid is the genetic material in living organisms that contain genes…
Q: 9. What is the female reproductive structure in a flower 1- Pistil 2- Sepal 3- Stamen 4- Petal
A: A flower is the reproductive component of a plant which have a stamen or pistil, or perhaps both, as…
Q: (1) Identify the type of pollution. (ii) Name one pollutant that causes the above pollution. (iii)…
A: 1) By going through the pic it seems it is water pollution.
Q: Is it advisable for a young man to start having sex during puberty?
A: Puberty is time in your life when boy or girl becomes mature for sex.These phase happened in every…
Q: Question 15 Juan used the ABO blood testing kit to determine his blood type. His test showed the…
A: The question is asked about the blood group based on the findings that the person named Juan have…
Q: 31. What are the shape of lymph nodes? 32. What is another name for innate immunity. 33. What do…
A: INTRODUCTION Answers of question 31 to 37 except 34 is given below. 34th question is incomplete.
Q: Why is an understanding of biogeochemical cycles essential in environmental scienc
A:
Q: When 6 molecules of glucose enter glycolysis, how much ATP molecules are prdouced?
A:
Q: There is a suspicion that human remains have been found at a Surface Burial site. What specific…
A: Forensic science is involved with the gathering and evaluation of physical evidence as well as other…
Q: Please explain clearly on the upstream and downstream process that involve in this pathway.
A: Fermentation technology is widely used to produce a variety of economically important compounds and…
Q: What are Chargaff’s rules? (in DNA and RNA model
A: DNA: DNA is a polymer made up of two polynucleotide chains that coil around each other to form a…
Q: Which of these biobeacons is most likely to gain traction in the years to come? Do you prefer…
A: Bioinformatics is the study and use of biological information's complexities. Bioinformatics…
Q: Which of the following is NOT an example of an intermediate filament? A Neurofilaments in…
A: The cytoskeleton is an extensive structure that provides shape, strength, and motility to a cell.…
Q: Question: If there 12 molecules of glucose that will enter the glycolytic pathway, how much ATP…
A: The number of ATP molecules synthesised by organisms having 10c subunits in their Fo complex from 12…
Q: 6. The anther and filament make up the 1- Pistil
A:
Q: Explain how you could use a test cross to help you determine the genotype of the purple flower with…
A: When attempting to determine if an organism is heterozygous or homozygous for a dominant trait, it…
Q: Who was Gregor Mendel? Describe the plant that he performed his research with and explain at least…
A: Gregor Johann Mendel was a meteorologist, mathematician, biologist, Augustinian friar and abbot of…
Q: If two Aa parents have four children then on average the predicted number of children with each…
A: Genotype is an individual's collection of genes. Phenotype refers to an individual's physical…
Q: Which of the seven chromosomal pairs that Mendel's genes were located?
A: The seven traits which Mendel used to study are Height Pod Shape Seed Shape Pea Colour Flower…
Q: OFFSPRING PHENOTYPE/GENOTYPE DETERMINATION Complete the following table and list all of the possible…
A: The word "genetic variation" refers to differences in the DNA sequences of our genomes.
Q: Match the following descriptions to the given choices. The first molecule in the biosynthesis of…
A: ANSWER) The first molecule in the biosynthesis of steroids that contains…
Q: arasitic organisms do you consider beneficial? F
A:
Q: 1. In a test cross, a homozygous recessive parent (mm) and a homozygous dominant parent (MM) are…
A: Note - We are supposed to answer 3 subparts of a question. Please repost other questions separately.…
Q: Bacteremia (infection in the blood) is severe because the pathogens move quickly with the blood…
A:
Q: true/false 1. Siphonaptera has a laterally flattened body. 2. Sawflies have crochets on their…
A: The answers is given below
Q: ? 1. mRNA is formed with codons as product ons are translated and polypeptide chain is tr es into…
A: Genetic material- DNA and RNA acts as the genetic material in most of the organisms . DNA stands…
Q: Figure 7. This image corresponds to question 22. 22a. What is the tissue type? 22b. What are the…
A: Introduction Tissue is a collection of cells with similar structures that work together as a unit.…
Q: 5- a sample of a crude protein extract is obtained from a prostate cancer tissue read 0.98 at 280 nm…
A: According to Christian and Warburg method, if the sample have the *presence of nucleic acid also,…
Q: what are the physiological changes you expect if you begin to runat a pace of10km/hr for 5 minutes…
A: Physiological changes have a tendency to increase the rate of heart along with the breadth rate.…
Q: What are the differences of replication of virus and replication of HIV?
A: Virus It is a submicroscopic infectious agent. It can replicate only inside the living cells.…
Q: Gene duplication
A: Gene Duplications arise from an event termed unequal crossing-over that occurs during meiosis…
Q: 4. In the garden pea, yellow cotyledon color is dominant to green, and inflated pod shape is…
A: Introduction:- Let us consider two attributes Cotyledon color pod shape From the given data it…
Q: 14. The thin stalk of the stamen Anther 1- Style Stigma Filament 2- 3- 4-
A: Pollination refers to the transfer of pollen grains from the anther of male flowers to the stigma of…
Q: Substrate cycling does not violate the laws of thermodynamics in making both directions of a…
A: In the third step of glycolysis, fructose-6-phosphate is converted to fructose- 1,6-bisphosphate .…
Q: What types of teeth are in the human body
A: As per our company's guidelines we are supposed to answer a single question at a time only. Please…
In your own words:
Describe the molecular mechanisms involved in P53’s role as a tumor repressor protein.
Step by step
Solved in 2 steps
- Describe the molecular mechanisms involved in P53’s role as a tumor repressor proteinHow is apoptosis involved in cancer? Describe the role of apoptosis in cancer and identify what molecules are involved. Cite your references. asap.Tumor suppressor proteins can assist in slowing down the cell cycle under appropriate conditions. In humans, the TP53 gene encodes a tumor suppressor called p53. Most mutations in the TP53 gene result in a mutant form of p53 that can no longer function to slow down the cell cycle, which can lead to a cell becoming cancerous. However, some mutant forms of p53 actually possess the ability to increase a cell's resistance to anticancer treatments. Which of the following BEST describes the latter type of mutation? loss-of-function mutation gain-of-function mutation suppressor mutation reverse mutation
- p53 is a tumor suppressor gene in human cells. Transcription of this gene leads to the production of the p53 protein in cells which modulates many signal pathways that lead to anti-tumor effects. The strength of anti-tumor effects is directly porportional to the accumulation of the protein within the cells of the person. Suppose a pediatric patient was recently admitted for a rare lung cancer related to p53 deficiencies (although the p53 itself is not mutated). Armed with your knowledge about the different mechanisms which govern transcription and translation, what are some potential reasons for the deficiency in p53 levels and how can you restore them if the reason you assumed for the deficiency is not directly reparable (i.e if you assume that protein degradation is too fast, you cannot directly repair protein degradation but you may want to increase transcription & translation rates to compensate)? Will your hypothesized repair(s) cause negative impacts to the cell? Why?The deregulation of several signal transduction pathways is integral to the onset of cancer. These pathways involve both tumor promoters (the "gas pedals") and tumor suppressors (the "brake pedals"). Which would be a more effective treatment for cancer: A small molecule inhibitor that targets a tumor suppressor or one that targets a tumor promoter? Briefly explain your choice. (THIS CAN BE DONE IN LESS THAN TWO SENTENCES, AND MINIMALLY IN ABOUT EIGHT WORDS.) Edit View. Insert Format Tools Table 12pt v Paragraph BI UAV 2VT² V| :Describe the effects of the over-expression of mdm2 on cell proliferation and apoptosis on cell signaling pathways and metabolism or cell cycle control. Briefly explain the normal role of each component in the context of the pathway and why its loss or modification would have the expected effect.
- Describe the general process of cell signalling pathways: what events take place for a signal to cause cellular changes? Provide examples and how perturbation of these events can result in “cancer pathways”. In addition, describe in detail a typical cancer pathway and its strategy to activate gene expression. What is the origin of many cancer pathways, i.e., during which stage of an organism’s live process(es) are they physiologically activated? Why is this important for cancer development?Describe the effects of the mutation causing the p21 promoter to no longer bind p53 on cell signaling pathways and metabolism or cell cycle control.The best strategy for treating a specific type of human tumor can depend on identifying the type of cell that became cancerous to give rise to the tumor. For some tumors that have colonized a distant location (metastasized), identifying the parental cell type can be difficult. Because the type of IF protein expressed is cell-type-specific, using monoclonal antibodies that react with only one type of IF protein can help in this identification. What IF proteins would you produce monoclonal antibodies against to identify (a) a sarcoma of muscle cell origin, (b) an epithelial cell carcinoma, and (c) an astrocytoma (glial cell tumor)?
- p53 is a tumor suppressor gene in human cells. Transcription of this gene leads to the production of the p53 protein in cells which modulates many signal pathways that lead to anti-tumor effects. The strength of anti-tumor effects is directly porportional to the accumulation of the protein within the cells of the person. Suppose a pediatric patient was recently admitted for a rare lung cancer related to p53 deficiencies (although the p53 itself is not mutated). what are some potential reasons for the deficiency in p53 levels and how can you restore them if the reason you assumed for the deficiency is not directly reparable (i.e if you assume that protein degradation is too fast, you cannot directly repair protein degradation but you may want to increase transcription & translation rates to compensate)? Will your hypothesized repair(s) cause negative impacts to the cell? Why?D) The level of carbon dioxide increases with the level of available oxygen. 60) The TP53 gene provides instructions for making a protein called tumor protein p53. Known as the guardian of the genome, this protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing too fast or in an uncontrolled way. The p53 protein is located in the nucleus of cells throughout the body, where it attaches directly to DNA and plays a critical role in determining whether the DNA will be repaired or the damaged cell will self- destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. eg Suppose chromosomes in a skin cell are damaged by ultraviolet radiation. If the damaged genes do not affect p53, which choice correctly predict if the cell will become cancerous and why? No, the cell will…List the regulatory mechanisms that might be lost in a cell producing faulty p53.