Describe how positive and negative selection leadsto a population of T cells that react to MHC molecules inassociation with nonself antigens, but not self antigens, andwhat happens when tolerance to self antigens is lost.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Describe how positive and negative selection leads
to a population of T cells that react to MHC molecules in
association with nonself antigens, but not self antigens, and
what happens when tolerance to self antigens is lost.

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